Leiomyosarcoma of kidney.

The case of a seventy-one-year-old woman with leiomyosarcoma of the kidney capsule is presented. Despite lack of invasion into surrounding tissues and few mitoses, the tumor recurred thirteen months after nephrectomy. A full subjective response and an almost complete objective regression lasting eight months were achieved using a short course of combination chemotherapy.

Neonatal intestinal perforation caused by congenital defects of the intestinal musculature.

Spontaneous perforation of the small intestine in the newborn is rare. In most cases the etiology is unknown. Three cases of perforation in preterm newborn infants are described.

The influence of lower urinary tract infection on the recurrence rate of superficial transitional cell carcinoma of the bladder.

We studied retrospectively 78 patients with recurrent superficial bladder tumors in an effort to determine whether transitional tumor cells implant and grow preferentially in patients who have undergone endoscopic resection of stage T1 bladder tumors in the presence of an inflamed urothelium. Of the patients 32 (group 1) had an undetected lower urinary tract infection at the time transurethral resection was performed and 46 (group 2) were free of infection. All patients had intravesical chemotherapy by thiotepa (triethylenethiophosphoramide) and were treated with appropriate antibiotics as soon as the urinary tract infection was recognized from 24 to 48 hours postoperatively.

Prostatic transitional cell carcinoma: concept of its pathogenesis and classification.

An updated comprehensive classification of transitional cell carcinoma (TCC) of the prostate is presented in accordance with the current nomenclature, which is based mainly on the theory of multifocal origin of urothelial neoplasms. TCC of the prostate is classified as being primary, secondary (synchronous and metachronous) or mixed (TCC associated with adenocarcinoma). The case histories of six patients with TCC of the prostate are presented.

Nonpapillary lesions of the urinary bladder: a retrospective study.

The histological and clinical features of nonpapillary bladder lesions in 53 patients are described. There were 8 patients (Group A) with atypical hyperplasia and/or carcinoma in situ, 16 patients (Group B) with nonpapillary invasive transitional cell carcinoma, and 29 patients (Group C) with nonpapillary bladder lesions and synchronous or metachronous papillary tumors. These lesions were usually represented clinically by irritative urinary symptoms, such as frequency, urgency, dysuria and hematuria.

Liver enlargement in long-term hemodialysis patients.

Hepatomegaly was observed in most of the patients undergoing long-term hemodialysis treatment. This was confirmed and quantitated by isotope liver scanning. Liver size was normal in uremic nondialyzed patients.

Early cervical pregnancy: ultrasonic diagnosis and conservative treatment.

Five cases of cervical pregnancy collected over an 8-year period (1971--1978) are analyzed. The incidence of cervical pregnancy at this institution is 1:7040 pregnancies. All cases were diagnosed prior to 12 weeks' gestation, and conservative treatment was instituted in each case.

Rupture of a renal angiomyolipoma (hamartoma).

A 54-year-old woman with spontaneous rupture of angiomyolipoma is presented. The literature on the 2 types of angiomyolipoma, without and with association of tuberose sclerosis, their rarity and the difficulties in their diagnoses, is reviewed.

Cystic hamartoma of the liver.

A case of cystic hamartoma of the liver is reported. The clinical presentation and management is discussed. A review of the origin of this rare tumor and its clinical and pathological characteristics is made.

Aberrant adrenal tissue in the wall of a hernial sac.

An aberrant adrenal, which is a supplementary to the normal adrenal, was found in the apex of hernial sacs in ten out of 350 operated children. This tissue contains adrenal cortex, which tends to atrophy and disappear during childhood, but uncommonly may persist into adult life. Rarely it may secrete abnormally or undergo neoplastic changes.

The central nervous system in a case of neurolathyrism.

We examined the central nervous system of a 67-year-old man who showed symptoms of lathyrism after being imprisoned at age 35 and fed on a diet of chick peas, Lathyrus sativus. The most obvious changes were loss of axons and myelin in the pyramidal tract in the lumbar spinal cord. These alterations correlated with spastic paraparesis.

Variability of splenomegaly in Crohn's disease.

Splenomegaly is an unusual finding in Crohn's disease and can be persistent or transient. In three febrile patients it was so prominent that the diagnosis of lymphoma was considered. In two additional patients the splenomegaly was an incidental finding.

Benign osteoblastoma of the calcaneous.

This is a case report of a 29-year-old male with a chondroblastoma of the os calcis successfully treated by almost total resection of the tuber calcanei without sacrifice insertion of the tendon achilles.