Biopsy of the proximal nail fold in collagen diseases.

A research procedure used to study proximal rail folds in connective tissue diseases is described. The technique is simple and one that is suitable and agreeable to patients. It affords study of tissue from the proximal nail fold in three different ways, namely, light microscopy with histochemistry, electron microscopy, and direct immunofluorescence.

[Cutaneous manifestations in disseminated intravascular coagulation syndrome].

The principal cutaneous manifestations indicating the need to seek intravascular coagulation are: purpura fulminans, extensive sheets of purpura, acralcyanosis, gangrene in a plaque distribution and perhaps, acute necrosis of the digits. The biological, anatomo-pathological and immunological signs of the conditions should be detected early and precisely by virtue of its nature as a medical emergency. The diversity of its clinical manifestations would seem to be related to the greater or lesser extent of the coagulopathy and resultant thrombosis in the microcirculation.

[Psoriasiform epidemic nevus or lineal psoriasis? Report of a case].

The authors describe a case of epidermic naevus with psoriasiform histology in a 27 year old female. Lesions had existed from birth. There is discussion of the differencial diagnosis with linear psoriasis.

Langerhans cells in actinic reticuloid.

Actinic reticuloid was observed in a patient following the development of porphyria cutanea tarda. A cutaneous lymphoma-like infiltrate was found histologically and at the ultrastructural level. In the infiltrate, the main population was histiocytic, with some mast cells and mononuclear cells.

[Malignant histiocytic reticulosis. Effect of bleomycin by intra-arterial route. Report of a case].

A case of malignant histiocytary lymphoma treated with Bleomycyn in a 78 year old patient is reported. The results were good but not durable.