Publications by authors named "Schocket L"

Purpose: To the best of our knowledge, implementation of artificial intelligence (AI)-based vision screening in community health fair settings has not been previously studied. This prospective cohort study explored the incorporation of AI in a community health fair setting to improve access to eyecare.

Methods: Vision screening was implemented during a community health fair event using an AI-based non-mydriatic fundus camera.

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Purpose: Multiple myeloma (MM) is a plasma cell dyscrasia leading to proliferation of monoclonal plasma cells. Ocular involvement in multiple myeloma is uncommon but can occur. The ocular manifestations of MM may include the cornea, uvea, and retinal vasculature.

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Article Synopsis
  • Extra-intestinal manifestations (EIMs) of inflammatory bowel diseases (IBD) are common but lack standardized definitions, diagnostic strategies, and treatment approaches.
  • An interdisciplinary expert panel utilized a modified Delphi consensus to develop definitions and guidelines for diagnosing and managing five major EIMs: erythema nodosum, pyoderma gangrenosum, uveitis, peripheral arthritis, and axial arthritis.
  • The resulting consensus criteria aim to improve clinical practice and guide future research on EIM management through clear diagnostic criteria, specialist identification, and suggested monitoring practices.
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Introduction: The dexamethasone (DEX) implant is an FDA approved treatment for diabetic macular edema, non-infectious posterior uveitis, and macular edema secondary to branch or central retinal vein occlusions. We describe a case of anterior chamber (AC) migration of a DEX implant in a patient with a history of congenital glaucoma and perform a review of the literature on this particular complication, summarizing the common risk factors, subsequent complications, and management options.

Case Description: A 46-year-old female with a history of congenital glaucoma, status post cataract extraction with insertion of intraocular lens, pars plana vitrectomy, and Baerveldt tube implant in the left eye was referred for post-operative cystoid macular edema (CME).

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Purpose: We assessed the image quality and reproducibility of blood flow measurements from a novel handheld laser speckle imager in handheld and stabilized use cases.

Methods: Eleven dilated human subjects were imaged with the XyCAM Handheld Retinal Imager investigational device (XyCAM HRI) in the handheld and stabilized use case in nine consecutive imaging sessions. Subjects then underwent standard color fundus photography using a Topcon TRC 50DX.

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Purpose: To report a case of acute retinal necrosis in a patient on anti-tumor necrosis factor α immunosuppressive therapy.

Methods: Case report.

Results: A 47-year-old man with psoriasis presented with blurred vision and floaters in the left eye 4 days after receiving his fourth dose of adalimumab, a tumor necrosis factor α antagonist.

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Background/purpose: Postmarket analysis helps identify potentially important side effects not discovered during clinical trials. Ocriplasmin is a recently approved medication administered by intravitreal injection for the treatment of symptomatic vitreomacular adhesion and macular hole. Overall, clinical trials of ocriplasmin have shown a relatively high safety profile.

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Objective: To assess microstructural changes in the retina that may explain incomplete visual recovery after anatomically successful repair of rhegmatogenous retinal detachments (RD) using ultrahigh-resolution optical coherence tomography (UHR OCT).

Design: Retrospective observational case series.

Participants: Seventeen patients with decreased visual acuity after RD repair.

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Purpose: To determine whether laser treatment applied according to the complications of age-related macular degeneration prevention trial (CAPT) has an effect on the choroidal circulation.

Design: Randomized controlled trial.

Methods: This study included 30 CAPT patients with bilateral drusen.

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Aims: To assess the effect of systemic hypertension on the choroidal circulation in subjects with a normal eye examination.

Methods: Laser Doppler flowmetry was used to determine relative choroidal blood velocity (Ch(vel)), volume (Ch(vol)), and flow (Ch(flow)) in the centre of the fovea. Measurements were obtained in 15 eyes of 15 subjects with systemic hypertension.

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Purpose: We studied the choroidal circulation in patients with proliferative diabetic retinopathy (PDR) to assess whether choroidal hemodynamic abnormalities may exist in PDR.

Methods: Eighteen eyes of 18 patients with PDR and high-risk characteristics for visual loss were included in this study. Mean duration of diabetes was 20 +/- 9 years (mean +/- SD), hemoglobin A1c was 8.

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Aim: Previous studies have suggested that laser photocoagulation therapy is associated with the resolution of drusen in some age related macular degeneration (AMD) patients. The main aim of the study was to determine whether low intensity laser treatment applied according to the Complications of AMD Prevention Trial (CAPT) protocol produces changes in the choroidal circulation that may help explain the mechanism leading to the resolution of drusen material.

Methods: This ancillary study included 30 CAPT patients with bilateral drusen that were treated and followed at the University of Pennsylvania.

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Purpose: To report the case of a 58-year-old man with sequential bilateral retrolaminar leukemic infiltration of the optic nerves who presented with normal-appearing optic nerves and no optic nerve enhancement.

Design: Interventional case report.

Methods: A 58-year-old man with chronic myelogenous leukemia (CML) developed progressive vision loss to no light perception in both eyes over four days.

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Purpose: To describe a 71-year-old man with bilateral primary adrenal lymphoma with metastases to the choroid.

Design: Interventional case report.

Methods: A 71-year-old man presented with decreased visual acuity in his left eye secondary to an exudative retinal detachment.

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Purpose: To evaluate the effects of felodipine, a calcium channel blocker, on ocular circulation.

Methods: In a double blind, randomized, crossover design, 10 volunteers received placebo or felodipine on 2 separate days. Bidirectional laser Doppler velocimetry (BLDV), laser Doppler flowmetry (LDF), and monochromatic fundus photography (MFP) were employed to assess retinal, choroidal, and optic nerve rim circulatory parameters.

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Purpose: To investigate retinal circulatory changes that occur during the third trimester of pregnancy in diabetic patients and control subjects.

Methods: Bidirectional laser Doppler velocimetry and monochromatic fundus photography were used to assess the retinal circulation in seven pregnant diabetic patients and 13 age-matched pregnant control subjects. Retinal venous diameter (D), maximum erythrocyte velocity (Vmax), and retinal volumetric blood flow rate (Q) were measured in one eye of each subject during the third trimester of pregnancy (DPREG, VmaxPREG, and QPREG, respectively).

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Background: The factors contributing to blood transfusions in patients with anemia of chronic disease are not well documented in the literature. We analyzed all blood transfusion events within a single oncology practice to determine if certain chemotherapy drugs, cancer types, or other factors necessitated more frequent transfusions.

Patients And Methods: Out of 331 patients receiving chemotherapy, 103 (31%) patients received a blood transfusion in 1995.

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Anomalous origin of the left coronary artery from the pulmonary artery was diagnosed in an infant girl who had evidence of transmural myocardial infarction of the free wall of the left ventricle. At age 13 months, she underwent a palliative left Vineberg implant, and remained asymptomatic until she was 8 years of age. At that time, she underwent suturing of the left coronary ostium for obliteration of the left coronary shunt at the pulmonary artery.

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