Impact of lipophilic antioxidants and level of antibodies against oxidized low-density lipoprotein in Polish children with phenylketonuria.

The treatment of phenylketonuria (PKU) patients constitutes a phenylalanine (Phe) intake restriction in their diet, which is achieved by adding a special Phe-free amino acid mixture to the diet. It has been reported that this diet could have some micronutrient deficiency. Several authors have also reported an increased oxidative stress or impaired antioxidant status in human and experimental PKU.

Quality of life in noncompliant adults with phenylketonuria after resumption of the diet.

Background: Discontinuation of dietary therapy in adults with phenylketonuria can lead to neuropsychological abnormalities and emotional problems. The aim of our study was to assess the change in quality of life in adult patients returning to the diet and to define the reasons for failure in diet resumption.

Methods: Quality of life was assessed by means of the Psychological General Well-Being Index before study entry and subsequently after 3 and 9 months.

[Visual evoked potentials in children cured with sodium-calcium versenate because of high blood lead level--the prospective study].

Purpose: To find out if blood lead level (Pb-B) changes have influence on visual evoked potentials.

Material And Methods: 18 children (36 eyes) treated with CaNa2EDTA because of chronic environmental lead poisoning were examined two times: first at age 2-15.5 (mean 8) years and second 4 years later.

[Visual evoked potentials in children with high blood lead level].

Purpose: The aim of this study is to find the relationship between lead level in blood (Pb-B) and visual evoked potentials (VEP) in children, environmentally exposed to lead.

Material And Methods: 32 children (64 eyes) with no clinical signs of lead poisoning were examined. Corrected visual acuity was 5/5 in all eyes.

[Serum leptin levels in children with chronic renal failure on continuous ambulatory peritoneal dialysis and on hemodialysis treatment].

Unlabelled: Malnutrition and loss of appetite remain a frequent problem in children with chronic renal failure (CRF). Recent studies in human gave much attention for leptin, polypeptide produced by adipocytes, and its influence on appetite and energetic balance regulation. The study aimed at evaluation of serum leptin levels (SLL) in children with CRF with regard to applied method of treatment.

[Treatment of chronic hepatitis with interferon in children with kidney diseases].

Unlabelled: The study aimed at evaluation of chronic hepatitis treatment results in children previously treated from nephrological indications in 1994-2002 years.

Material And Methods: Examination was performed in 42 children in the age 10.2 +/- 4.

[Interferon therapy in cildren with chronic hepatitis and chronic renal failure treated with dialysis].

The HCV proliferation occurs in patients with chronic hepatitis type C on hemodialysis treatment after the kidney graft. The replication markers of HBV also occurs in patients after kidney graft. 35 children were examined.

[Physiological and pathophysiological role of histamine in the gastrointestinal tract].

In this paper, the authors discuss problems concerning the role played by histamine in various physiological and pathological processes in the gastrointestinal tract. The synthesis and metabolism of histamine is described. Apart from participation in many physiological processes, e.