Publications by authors named "Schmitz G"

Atmospheric contaminants from natural processes and anthropogenic activities pose a major problem to the environment. Here we analyze the dynamics of atmospheric and terrestrial contaminant concentrations in sediments containing chemical elements, such as nanoparticles (NPs) and ultrafine particles in hydrological sources of the Caribbean region of Colombia. Terrestrial sediments were collected from 2022 to 2024, and quantified for major chemical elements in the form of NPs and ultrafine particles in runoff receiving areas along the banks of Colombia's Ciénaga Grande in Santa Marta Bay, on the Isla de Salamanca.

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For ultrasound localization microscopy, the localization of microbubbles (MBs) is an essential part to obtain super-resolved maps of the vasculature. This paper analyzes the impact of image discretization and patch size on the precision of different MB localization methods to reconcile different observations from previous studies, provide an estimate of feasible localization precision, and derive guidelines for an optimal parameter selection. For this purpose, images of MBs were simulated with Gaussian point-spread functions (PSF) of varying width parameter σ at randomly generated subpixel positions, and Rician distributed noise was added.

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Ultrasound localization microscopy is becoming well established in preclinical applications. For its translation into clinical practice, the localization precision achievable with commercial ultrasound scanners is crucial - especially with volume imaging, which is essential for dealing with out-of-plane motion. Here, we propose an easy-to-perform method to estimate the localization precision of 3D ultrasound scanners.

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Article Synopsis
  • * An unusual DSA pattern was observed initially, which improved and resolved after four treatments, correlating with the clinical alleviation of symptoms.
  • * The findings indicate that BIS-DSA monitoring could serve as an effective and affordable method for neuro-monitoring during hyperbaric oxygen therapy in patients with decompression sickness.
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Microbubbles (MB) are widely used as contrast agents for ultrasound (US) imaging and US-enhanced drug delivery. Polymeric MB are highly suitable for these applications because of their acoustic responsiveness, high drug loading capability, and ease of surface functionalization. While many studies have focused on using polymeric MB for diagnostic and therapeutic purposes, relatively little attention has thus far been paid to improving their inherent imaging and drug delivery features.

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It is the purpose of this review to compare differences in postnatal epigenetic programming at the level of DNA and RNA methylation and later obesity risk between infants receiving artificial formula feeding (FF) in contrast to natural breastfeeding (BF). FF bears the risk of aberrant epigenetic programming at the level of DNA methylation and enhances the expression of the RNA demethylase fat mass- and obesity-associated gene (), pointing to further deviations in the RNA methylome. Based on a literature search through Web of Science, Google Scholar, and PubMed databases concerning the dietary and epigenetic factors influencing gene and FTO protein expression and FTO activity, FTO's impact on postnatal adipogenic programming was investigated.

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Introduction: In the 2023 National Resident Matching Program (NRMP) match, there were 554 unfilled emergency medicine (EM) positions before the Supplemental Offer and Acceptance Program (SOAP). We sought to describe features of EM programs that participated in the match and the association between select program characteristics and unfilled positions.

Methods: The primary outcome measures included the proportion of positions filled in relation to state and population density, hospital ownership type, and physician employment model.

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Lipidome perturbation occurring during meta-inflammation is associated to left ventricle (LV) remodeling though the activation of the NLRP3 inflammasome, a key regulator of chronic inflammation in obesity-related disorders. Little is known about phosphatidylcholine (PC) and phosphatidylethanolamine (PE) as DAMP-induced NLRP3 inflammasome. Our study is aimed to evaluate if a systemic reduction of PC/PE molar ratio can affect NLRP3 plasma levels in cardiovascular disease (CVD) patients with insulin resistance (IR) risk.

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The water treatment depends exclusively on the identification of residues containing toxic chemical elements accumulated in NPs (nanoparticles), and ultrafine particles sourced from waste piles located at old, abandoned sulfuric acid factories containing phosphogypsum requires global attention. The general objective of this study is to quantify and analyze the hazardous chemical elements present in the leachate of waste from deactivated sulfuric acid factories, coupled in NPs and ultrafine particles, in the port region of the city of Imbituba, Santa Catarina, Brazil. Samples were collected in 2020, 2021, and 2022.

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With the widespread interest and uptake of super-resolution ultrasound (SRUS) through localization and tracking of microbubbles, also known as ultrasound localization microscopy (ULM), many localization and tracking algorithms have been developed. ULM can image many centimeters into tissue in-vivo and track microvascular flow non-invasively with sub-diffraction resolution. In a significant community effort, we organized a challenge, Ultrasound Localization and TRacking Algorithms for Super-Resolution (ULTRA-SR).

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It is shown herein that Perrot et al., who reviewed delay-and-sum beamforming for ultrafast ultrasound imaging in [Ultrasonics 111 (2021) 106309], misinterpreted the purpose of dynamic receive apertures. Such apertures widen with the focal length as a function of a given f-number and improve the image quality by suppressing grating lobes.

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Turfing is a colloquialism that refers to what clinicians do to patients whose needs do not fit neatly and tidily into typical clinical placement protocols, especially during inpatient admissions from a hospital's emergency department. This term and this practice are both clinically and ethically problematic because a patient is rarely, if ever, "turfed" to their advantage. Ethically speaking, turfing constitutes deferral of responsibility for a patient's admission or care to colleagues.

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The perception of effort is elementary for the self-regulation of exercise intensity in sports. The competence for rating perceived effort (RPE) seems to be related to physical and cognitive development. Children accurately rate perceived effort during incremental exercise tests when loads progressively increase, but it remains unclear how children perform when they participate in sports games, which are characterized by complex tasks with varying intensity profiles.

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Article Synopsis
  • - Psychedelic drugs like LSD and psilocybin show promise as treatments for various mental health issues, including depression and PTSD, by activating specific brain receptors (HTR2A).
  • - Researchers developed engineered mice to help map and study HTR2A receptors and the neurons that express them, allowing for a clearer understanding of how these psychedelics work in the brain.
  • - Behavioral experiments confirmed that psychedelics affect these mice as expected, and further electrical activity studies showed how a neurotransmitter (5-HT) impacts neuron firing, paving the way for deeper insights into the effects of psychedelics.
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Objective: Ultrasound localization microscopy (ULM) has gained increasing attention in recent years because of its ability to visualize blood vessels at super-resolution. The field of oncology, in particular, could benefit from detailed vascular characterization, for example, for diagnosis and therapy monitoring. This study was aimed at refining ULM for breast cancer patients by optimizing the measurement protocol, identifying translational challenges and combining ULM and shear wave elastography.

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Measles, or rubeola, is a highly contagious acute febrile viral illness. Despite the availability of an effective vaccine since 1963, measles outbreaks continue worldwide. This article seeks to provide emergency physicians with the contemporary knowledge required to rapidly diagnose potential measles cases and bolster public health measures to reduce ongoing transmission.

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We present a new program implementation of the Gaussian process regression adaptive density-guided approach [Schmitz et al., J. Chem.

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Ultrafast imaging modes, such as coherent plane-wave compounding (CPWC), increase image uniformity and reduce grating lobe artifacts by dynamic receive apertures. The focal length and the desired aperture width maintain a given ratio, which is called the F -number. Fixed F -numbers, however, exclude useful low-frequency components from the focusing and reduce the lateral resolution.

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The global transition from fossil fuels to green energy underpins the need for efficient and reliable energy storage systems. Advanced analysis and characterization of battery materials is not only important to understand fundamental battery properties but also crucial for their continued development. A deep understanding of these systems is often difficult to obtain through only pre- and/or post-mortem analyses, with the full complexity of a battery being hidden in its operational state.

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Right ventricular (RV) free wall longitudinal strain (RVFWLS), and four-chamber longitudinal strain (RV4CLS) using speckle tracking echocardiography have demonstrated increased accuracy and discrimination to measure right ventricular function in different clinical conditions. Reproducibility data of these measures are scarce and mainly tested in small or reference populations. The main objective of this study was to investigate their reproducibility, and of other traditional RV parameters, from unselected participants of a large cohort study.

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Ultrasound Localization Microscopy (ULM) is an emerging technique that provides impressive super-resolved images of microvasculature, i.e., images with much better resolution than the conventional diffraction-limited ultrasound techniques and is already taking its first steps from preclinical to clinical applications.

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Objective: To evaluate the pulp chamber temperature rise (PCTR) in light-cure bonding of brackets with and without primer, in intact and restored mandibular central incisors (M1), maxillary first premolars (Mx4), and mandibular third molars (M8).

Material And Methods: Ninety human teeth were included: M1 (n=30), Mx4 (n=30), and M8 (n=30). Light-cure bonding of brackets was performed in intact (n=60) and restored (n=30) teeth, with primer (n=60) or without (n=30) primer.

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Reactive wetting is a process ubiquitous in modern electronic soldering processes. Nonetheless, the dependencies of reactive wetting angles on surface roughness and droplet size are not well understood but become increasingly important for reliable miniaturization of devices. In this study, advancing contact angles of the Sn/Cu reactive solder system are investigated and the aforementioned dependencies are evaluated.

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