Carbon dots (CDs), a novel class of carbon-based nanoparticles, have received a lot of interest recently due to their exceptional mechanical, chemical, and fluorescent properties, as well as their excellent photostability and biocompatibility. CDs' emission properties have already found a variety of potential applications, in which bioimaging and sensing are major highlights. It is widely acknowledged that CDs' fluorescence and surface conditions are closely linked.
View Article and Find Full Text PDFFaults in photovoltaic (PV) modules may occur due to various environmental and physical factors. To prevent faults and minimize investment losses, fault diagnosis is crucial to ensure uninterrupted power production, extended operational lifespan, and a high level of safety in PV modules. Recent advancements in inspection techniques and instrumentation have significantly reduced the cost and time required for inspections.
View Article and Find Full Text PDFBackground: Vitamin D is associated with many skeletal-related processes in the body. A major health problem concerning decreased quality of life is chronic low back pain (LBP). Many studies have proved that chronic pain improves with Vitamin D supplementation.
View Article and Find Full Text PDFBackground: There are limited global data on head-to-head comparisons of vaccine platforms assessing both humoral and cellular immune responses, stratified by pre-vaccination serostatus. The COVID-19 vaccination drive for the Indian population in the age group 18-45 years began in April 2021 when seropositivity rates in the general population were rising due to the delta wave of COVID-19 pandemic during April-May 2021.
Methods: Between June 30, 2021, and Jan 28, 2022, we enrolled 691 participants in the age group 18-45 years across four clinical sites in India.
Two new species, Tetralicia sawyeri n. sp. and Aleuroplatus martini n.
View Article and Find Full Text PDFIndian J Crit Care Med
March 2024
Shrinath V, Marwah V, Jyothis MC. Analgo-sedation in Patients on Non-invasive Mechanical Ventilation: Need for Guideline Recommendation. Indian J Crit Care Med 2024;28(3):309-310.
View Article and Find Full Text PDFBackground Early diagnosis and prompt management are crucial for bacteremia and sepsis, as they have the potential to lead to septic shock and fatal outcomes. Bacteremia induces the recruitment of immature granulocytes (IGs) into the circulation, which indicates active bone marrow response. The goal of our present study is to determine the effectiveness of automated IG measurement as an alternate indicator for infection and also its clinical utility in predicting positive blood culture (BC) results.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
February 2024
Background: In a world filled with technology, there's concern about the impact of screen time on children and teenagers. A recent study of 11,875 children aged nine to 10 in the US explored how screen time affects mental health, behaviour, school performance, sleep, and friendships. The results indicate that more screen time is mildly linked to worse mental health, more behaviour problems, lower academic performance, and poorer sleep, but slightly better peer relationships.
View Article and Find Full Text PDFJ Imaging Inform Med
August 2024
Breast cancer is deadly cancer causing a considerable number of fatalities among women in worldwide. To enhance patient outcomes as well as survival rates, early and accurate detection is crucial. Machine learning techniques, particularly deep learning, have demonstrated impressive success in various image recognition tasks, including breast cancer classification.
View Article and Find Full Text PDFNanoscale Adv
February 2024
Carbon nanodots, the luminescent nanoparticles of carbon with size restriction below 10 nm, have attracted inordinate attention in materials science due to their widespread applications in optoelectronic and biological fields. Low toxicity and facile synthesis pathways render them favourites in the above-mentioned areas in the context of green chemistry. This work presents fine applications of -phenylenediamine-derived carbon nanodots (PD-CNDs) achieved a facile one-pot hydrothermal method.
View Article and Find Full Text PDFAim of this study is to assess the clinical efficacy of 445 nm Diode laser as an adjunct to Kirkland flap surgery in management of periodontitis. Type of study is a Split mouth clinical trial in which a total of 13 patients were recruited based on specific inclusion and exclusion criteria. In each participant, random allocation of selected sites into test and control in contralateral quadrants was done.
View Article and Find Full Text PDFNeural tube defects (NTDs) are the most common congenital anomalies of the CNS. It is widely appreciated that both genetic and environmental factors contribute to their etiology. The inability to ascribe clear genetic patterns of inheritance to various NTD phenotypes suggests it is possible that epigenetic mechanisms are involved in the etiology of NTDs.
View Article and Find Full Text PDFA novel multimode colorimetric and fluorescent chemosensor was developed using an 8-hydroxy quinoline carbaldehyde Schiff base with a quinoline hydrazide probe (E)-2-((2-(quinolin-2-yl)hydrazineylidene)methyl)quinolin-8-ol (L). NMR (H & C), FTIR, and HR-mass spectral characterization techniques confirmed the probe L structural conformation. As Probe L contacts Pb ions, a color change and turn-off emission can be visually detected in EtOH:HO (1:1, v/v, pH = 7.
View Article and Find Full Text PDFCancer is a complex disease that can affect different parts of the body. The rates of cancer have shown an increasing trend in the past decade. A majority of cancers are detected late, therefore becoming untreatable and resulting in significant mortality.
View Article and Find Full Text PDFDynamic interactions within the tumor micro-environment drive patient response to immune checkpoint inhibitors. Existing preclinical models lack true representation of this complexity. Using a Head and Neck cancer patient derived TruTumor histoculture platform, the response spectrum of 70 patients to anti-PD1 treatment is investigated in this study.
View Article and Find Full Text PDFHeavy metals (HMs) enter waterbodies through various means, which, when exceeding a threshold limit, cause toxic effects both on the environment and in humans upon entering their systems. Recent times have seen an increase in such HM influx incident rates. This requires an instant response in this regard to review the challenges in the available classical methods for HM detection and removal.
View Article and Find Full Text PDFBackground: An increasing incidence of colorectal cancer (CRC) is being reported in developing countries, including India. Most Indian studies on CRC are retrospective and single-centered. The present study is an attempt to understand the current clinical profile and stage of newly diagnosed CRCs across multiple centers in Tamil Nadu, India.
View Article and Find Full Text PDFIn view of the increased number of detected dengue cases in Bengaluru, a request for situation analysis was received from local health authorities in the selected area. The study included epidemiological and entomological assessments to understand the same. The immature forms collected were allowed to emerge, pooled, and processed for vector incrimination.
View Article and Find Full Text PDFBackground: A large number of illnesses that lack physical visibility are characterised by troubled clinical encounters. Endometriosis is one such condition with very real and often debilitating symptoms that remain invisible to the clinician's eye, but are experienced and lived by the patient.
Method: This paper probes into two first person accounts of endometriosis to find out how endometriosis patients experience health care.
Objectives: Neonatal myocarditis is a rare but life-threatening complication of enterovirus infection that presents like bacterial sepsis.
Outbreak: A sudden upsurge in cases of neonatal enteroviral myocarditis, reported from South West England and South Wales between June 2022 and April 2023 has alerted health agencies to bring in counteracting measures.
Impact: In view of this outbreak situation, the World Health Organisation advisory has urged clinicians seeing neonates and infants with shock may consider myocarditis as a differential diagnosis and test for enteroviruses.
Multi-Target Inhibitors are the upcoming frontrunners of the antibiotic world as they provide significant advantage over drug resistance development. Antibacterial drug discovery research, requires more robust and innovative approaches such as multi-target inhibiting drugs, which over comes the innate hurdles in the field of antibiotics. In this current study, a curated set of 5,112 phytochemical molecules were virtually screened for its multi-target inhibition potential against 7 antibacterial protein drug-targets.
View Article and Find Full Text PDFLung cancer is thought to be a genetic disease with a variety of unknown origins. Globocan2020 report tells in 2020 new cancer cases identified was 19.3 million and nearly 10.
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