Publications by authors named "Schlagenhauf P"
Disparities in response to mRNA SARS-CoV-2 vaccines according to sex and age: A systematic review.
New Microbes New Infect
February 2025
Background: The rapid development and distribution of mRNA COVID-19 vaccines has been essential in containing the SARS-CoV-2 epidemic around the globe. For ongoing and future immunization campaigns globally, there is a need to evaluate the impact of population demographics such as age and sex, on vaccine efficacy and safety.
Methods: This systematic review (PROSPERO ID CRD42023328245) conducted according to PRISMA guidelines evaluates the impact of age and sex on the safety and efficacy of the mRNA COVID-19 vaccinations administrated in 15 studies that were chosen according to strict criteria.
Introduction: Aedes-borne arboviral infections, both imported and autochthonous, are reported in Europe. We evaluated the landscape of these infections in Europe over 23 years and attempted to pre-empt the trajectory of impact of these infections in the climatic context of Aedes mosquito expansion in Europe.
Methods: This systematic review was conducted in accordance with PRISMA guidelines and registered in Prospero (CRD42023360259).
Article Synopsis
- * Two vaccines are available: Dengvaxia®, which is not recommended for travelers, and Qdenga®, which is now licensed for travelers in several European countries, including Switzerland.
- * The Swiss Expert Committee for Travel Medicine advises that Qdenga® should not be given to those without prior dengue infection, but may be suitable for travelers aged 6 and older who have proof of past infection and are going to areas with high dengue transmission.
Background: Although the recent literature indicates that mpox (monkeypox) primarily affects men, there are also multiple reports in women. Estimates of the sex distribution of mpox patients and patterns will enable a better understanding of the ongoing mpox outbreak.
Methods: In this systematic review and meta-analysis, seven databases were searched for studies published in English up to January 4, 2023.
Introduction: Current traveller health surveillance is 'top-down'. Mobile-based surveillance could capture infection symptoms in real time. We aimed to evaluate the spectrum of illness in travellers using a mobile app-based system.
View Article and Find Full Text PDFMonkeypox (mpox) is a significant health concern affecting children and adolescents globally. This systematic review and meta-analysis aims to synthesise the available evidence on the proportion of children and adolescents affected by the mpox virus. A comprehensive search was conducted in seven electronic databases (PubMed, Scopus, Web of Science, EMBASE, ProQuest, EBSCOHost, and Cochrane) to identify the original reports on mpox cases in children and adolescents till 15 January 2023.
View Article and Find Full Text PDFBackground: Respiratory tract infections (RTIs) are common in travellers due to the year-round or seasonal presence of respiratory pathogen and exposure to crowded environments during the itinerary. No study has systematically examined the burden of RTI infections among travellers. The aim of this systematic review and meta-analysis is to evaluate the prevalence of RTIs and symptoms suggestive of RTIs among travellers according to risk groups and/or geographic region, and to describe the spectrum of RTIs.
View Article and Find Full Text PDFBackground: Hair analysis to identify substance use is an established methodology. This could also be a method to monitor adherence to antimalarial drugs. We aimed to establish a methodology to determine hair concentrations of atovaquone, proguanil and mefloquine in travellers using chemoprophylaxis.
View Article and Find Full Text PDFBackground: The COVID-19 pandemic resulted in a sharp decline of post-travel patient encounters at the European sentinel surveillance network (EuroTravNet) of travellers' health. We report on the impact of COVID-19 on travel-related infectious diseases as recorded by EuroTravNet clinics.
Methods: Travelers who presented between January 1, 2019 and September 30, 2021 were included.
Background: The tick is the main vector of and tick-borne encephalitis virus in Switzerland Spotted fever group Rickettsiae (SFG) and have been detected in Swiss ticks, however, information about the extent and clinical presentation of these infections in humans is scant.
Methods: Indirect fluorescent antibody tests for SFG rickettsiae and were performed on serum samples of 121 seropositive patients with and without Lyme disease and 43 negative controls.
Results: Out of 121 seropositive individuals, 65 (53.
Rising temperatures pose a threat to malaria transmission in Europe. Anopheles vectors are becoming more stable and widespread, putting some areas at increased risk of transmission for extended periods. By 2030 or 2050, the period of susceptibility is expected to extend to 3-6 months in some European countries and Anopheles mosquitoes are expected to migrate northward.
View Article and Find Full Text PDFPurpose: To compare retinal changes in young adults with previous SARS-CoV-2 infection with healthy young controls using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA).
Methods: This prospective single-center study was conducted at the University Hospital of Zurich, Zurich, Switzerland. Participants were imaged from May to November 2021 using the device (Visionix International SAS, Pont-de-l'Arche, France).
Background: International travellers may seek care abroad to address health problems that arise during their trip or plan healthcare outside their country of residence as medical tourists.
Methods: Data were collected on travellers evaluated at GeoSentinel Network sites who reported healthcare during travel. Both unplanned and planned healthcare were analysed, including the reason and nature of healthcare sought, characteristics of the treatment provided and outcomes.