Background: The rate of survival to hospital discharge is less than 10% for out-of-hospital cardiac arrest (OHCA).
Aim: To develop and implement a Chilean prospective, standardized cardiac arrest registry following the Utstein criteria.
Material And Methods: We conducted a prospective registry for patients presenting at an urban, academic, high complexity emergency department (ED) after having an OHCA.
Bioelectronic devices that are tetherless and soft are promising developments in medicine, robotics and chemical computing. Here, we describe bioinspired synthetic neurons, composed entirely of soft, flexible biomaterials, capable of rapid electrochemical signal transmission over centimetre distances. Like natural cells, our synthetic neurons release neurotransmitters from their terminals, which initiate downstream reactions.
View Article and Find Full Text PDFFifteen procedures have been carried out in 14 patients using the Kensey rotation angioplasty system. Sixteen occlusions of the superficial femoral artery, with an average length of 10.2 cm (3 to 24 cm) and one artery with multiple stenoses were treated.
View Article and Find Full Text PDFAdrenalectomized rats displayed a deficiency in retention of an immobility response acquired during an initial 15-min forced swimming procedure (Porsolt swimming test) and measured 24 h later in a 5-min retest session. The deficit could be restored dose dependently with the glucocorticoid dexamethasone (microgram range) administered 15 min after the initial test. The antiglucocorticoid RU 38486 administered subcutaneously (1 and 10 mg/kg) inhibited the dexamethasone effect and caused a parallel shift in the dose-response curve of dexamethasone.
View Article and Find Full Text PDFThe proximal pars distalis (PPD) of the pituitary of the African catfish, Clarias gariepinus, was studied with immunocytochemical methods at the ultrastructural level. Anti-serum raised against synthetic mammalian luteinizing hormone-releasing hormone (LHRH) was applied on Lowicryl-embedded pituitaries and the antigenic sites were visualized with protein A-gold. In nerve fibers contacting the gonadotropic cells, granulated vesicles with a diameter of 90-120 nm were labeled after this procedure, whereas the glandular cells were not labeled.
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