Publications by authors named "Schaik D"

Background: Depressed patients who have become victim of violence are prone to revictimization. However, no evidence-based interventions aimed at reducing revictimization in this group exist.

Methods: This multicenter randomized controlled trial evaluated the effectiveness of an internet-based emotion regulation training (iERT) added to TAU in reducing revictimization, emotion dysregulation, and depressive symptoms in recently victimized, depressed patients compared to TAU alone.

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Introduction: Spinal pain syndromes have a severe impact on the patient's sex life, contributing to a decrease in sexual function and sexual satisfaction. Despite the importance of sexual health on mental and physical wellbeing, sexual health is rarely discussed during consultations.

Research Question: The aim of this study is to explore to what extent influencing factors can alter the discussion about sexual health during consultations.

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Objective: Interpersonal and social rhythm therapy (IPSRT) was developed to empower patients with mood disorders by stabilizing underlying disturbances in circadian rhythms and by using strategies from interpersonal psychotherapy. Group IPSRT has not been studied with a transdiagnostic sample of patients across the life span with either major depressive disorder or bipolar disorder.

Methods: Thirty-eight outpatients, ages 26-80, with major depressive disorder or bipolar disorder in any mood state were recruited from clinics in the Netherlands and were treated with 20 sessions (two per week) of group IPSRT.

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Article Synopsis
  • - Both antidepressant medication and running therapy are effective for treating depression and anxiety, but they might affect mental and physical health differently.
  • - In a study with 141 participants, remission rates after 16 weeks were similar for both treatments, but running therapy showed significant improvements in various physical health indicators like weight and blood pressure.
  • - The study had limitations, including a preference for running therapy among participants, which affected the sample size of each treatment group.
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Objective: Blended-format interpersonal psychotherapy (IPT) is an integrated approach consisting of alternating face-to-face (in person or videoconferencing) and online sessions, and this format may increase access to care, empower patients, and improve quality and cost-effectiveness of care. This study, conducted in the Netherlands, was one of the first to investigate the feasibility of blended-format IPT in specialized mental health care.

Methods: Participants (ages 18-64, N=21) with a unipolar depressive episode were recruited at an outpatient mood disorder clinic.

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Background: Discontinuation of antidepressant medication can be difficult due to withdrawal symptoms and relapse risk. Scientific evidence on the questions of who, when, and how to stop antidepressants is limited. In Amsterdam a multidisciplinary outpatient clinic was started to provide advice and guidance.

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Background: Depressed patients are prone to violent victimization, and patients who were victimized once are at increased risk to fall victim to violence again. However, knowledge on the context of victimization in depressed patients is lacking, and research identifying targets for prevention is urgently needed.

Methods: This cross-sectional study explored context characteristics, disclosure rates and gender differences regarding violent victimization in 153 recently victimized depressed patients.

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Background: Anxiety and depressive disorders are prevalent in adolescents and young adults. However, most young people with mental health problems do not receive treatment. Computerized cognitive behavior therapy (cCBT) may provide an accessible alternative to face-to-face treatment, but the evidence base in young people is limited.

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Insomnia in depressed patients is usually targeted by medication, while cognitive behavioural treatment for insomnia (CBT-I) is the treatment of first choice. Effective online CBT-I is available but is not frequently offered in regular care.
AIM: To determine the feasibility and indications for effectiveness of I-Sleep, an online CBT-I module, for uni- and bipolar depressed patients in specialised mental health care settings.

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(1) Background: Blended cognitive behavioral therapy (bCBT; online and face-to-face sessions) seems a promising alternative alongside regular face-to-face CBT depression treatment in specialized mental health care organizations. Therapists are key in the uptake of bCBT. This study focuses on therapists' perspectives on usability, satisfaction, and factors that promote or hinder the use of bCBT in routine practice; (2) Methods: Three focus groups ( = 8, = 7, = 6) and semi-structured in-depth interviews ( = 15) were held throughout the Netherlands.

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Background: Depressive and anxiety disorders have shown to be associated to premature or advanced biological aging and consequently to adversely impact somatic health. Treatments with antidepressant medication or running therapy are both found to be effective for many but not all patients with mood and anxiety disorders. These interventions may, however, work through different pathophysiological mechanisms and could differ in their impact on biological aging and somatic health.

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Background: Anxiety and depressive disorders are increasingly being viewed as chronic conditions with fluctuating symptom levels. Relapse prevention programmes are needed to increase self-management and prevent relapse. Fine-tuning relapse prevention programmes to the needs of patients may increase uptake and effectiveness.

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Background: This study aimed to identify subgroups for whom supported self-help preventive cognitive therapy (S-PCT) is more (cost)effective than treatment as usual (TAU) in preventing relapse and recurrence of major depression.

Methods: We conducted a randomized controlled trial in which 248 remitted, recurrently depressed participants were randomized to S-PCT (n = 124) or TAU (n = 124). Clinical outcome was relapse or recurrence of major depressive disorder (SCID-I).

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Article Synopsis
  • The DTUD is a newly developed Decision Tool aimed at identifying patients with Major Depressive Disorder (MDD) who require specialized care, addressing a significant gap in current treatment strategies.
  • The tool underwent a rigorous evaluation process, including a multicenter study with 243 participants, focusing on its reliability, clarity, and validation against existing measures of treatment resistance.
  • Results indicated that the DTUD is both efficient in administration and reliable, with a recommended cut-off score of ≥5 providing a good balance of sensitivity (67%) and specificity (83%) for identifying patients needing specialized care.
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Article Synopsis
  • The study aimed to improve long-term outcomes for patients with major depressive disorder by testing the effectiveness of preventive cognitive therapy (PCT) after cognitive behavioral therapy (CBT).
  • A trial involving 214 patients in remission from depression was conducted, comparing PCT with standard care, finding that PCT significantly delayed relapse over 15 months.
  • Although PCT helped in delaying relapse, it did not show a difference in the number or severity of relapses or residual symptoms compared to standard care.
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Childhood abuse is a major public health problem that has been linked to depression in adulthood. Although different types of childhood abuse often co-occur, few studies have examined their unique impact on negative mental health outcomes. Most studies have focused solely on the consequences of childhood physical or sexual abuse; however, it has been suggested that childhood emotional abuse is more strongly related to depression.

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Aims: Psychiatric patients are at increased risk to become victim of violence. It remains unknown whether subjects of the general population with mental disorders are at risk of victimisation as well. In addition, it remains unclear whether the risk of victimisation differs across specific disorders.

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Article Synopsis
  • - The study evaluates the cost-effectiveness of a supportive self-help therapy (S-PCT) combined with standard treatment (TAU) for preventing relapse in patients with a history of depression currently in remission.
  • - The findings show that S-PCT reduced relapse or recurrence of depression by 15%, but had higher societal costs, with mixed results regarding its cost-effectiveness based on willingness to pay thresholds.
  • - Ultimately, the research suggests that whether S-PCT is considered cost-effective depends on the decision-makers' willingness to pay, but overall, it may not be cost-effective compared to TAU.
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Background: Depressed patients are at increased risk to fall victim to a violent crime compared to the general population. It remains unknown whether their increased risk persists after remission. This study compared victimization rates of remitted patients with both a random general population sample and a group of currently depressed patients.

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Background: Psychiatric patients are at high risk of becoming victim of a violent crime compared to the general population. Although most research has focused on patients with severe mental illness, depressed patients have been demonstrated to be prone to victimization as well. Victimization is associated with more severe symptomatology, decreased quality of life, and high risk of revictimization.

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We report on the Belgian experience with the aMace® custom-made triflange acetabular component in revision total hip arthroplasty between September 2009 and November 2014. We focused on (1) the complexity of the preoperative planning and reimbursement procedure; (2) the surgical problems and operative experience; and (3) the early outcome. We collected 20 patients' reviews and 22 surgeons' reviews, with a mean follow-up of 25 months.

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Background: The burden and economic consequences of depression are high, mostly due to its recurrent nature. Due to current budget and time restraints, a preventive, low- cost, accessible minimal intervention is much needed. In this study, we evaluated the effectiveness of a supported self-help preventive cognitive therapy (S-PCT) added to treatment as usual (TAU) in primary care, compared to TAU alone.

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Background: Internet-based Cognitive Behavioural Therapy (iCBT) for the treatment of depressive disorders is innovative and promising. Various studies have demonstrated large effect sizes up to 2.27, but implementation in routine practice lags behind.

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Background: Internet-based interventions are seen as an important potential strategy to improve accessibility and affordability of high quality treatments in mental healthcare. A growing number of studies have demonstrated the clinical efficacy of internet-based treatment for mood disorders, but scientific evidence for the application in routine specialised mental healthcare settings is limited. Also, little is known about the clinical and health-economic benefits of blended treatment, where online interventions are integrated with face-to-face treatment of depression in one treatment protocol.

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