[Tasks and Expectations of the Medical Officer in the Statutory Health Insurance System].

Tasks and Expectations of the Medical Officer in the Statutory Health Insurance System The statutory health insurance OKP is based on the principle that all insured persons have equal access to the approved services. If so, why does it actually need the "medical officer"? What role is assigned to this professional title? What requirements must be met for working as a medical officer? What are the special challenges? This article will provide you with answers to these questions.

Leptin response to endogenous acute stress is independent of pituitary function.

There are close interactions between the adipocyte-derived hormone, leptin, and the anterior pituitary, especially the hypothalamic-pituitary-adrenal (HPA) axis. We investigated the relationship between the sympathetic adrenergic system and serum leptin levels, dependent on the function of anterior pituitary hormone axes, in 27 patients without a history of a hormone-secreting pituitary adenoma or other underlying endocrine disease. Based on responses in a routine insulin hypoglycemia test (ITT), the patients were classified as hypopituitary (HP; n=15), growth hormone deficient (GHD; n=6) or controls (CTR; 6 patients with normal responses).

Leptin levels in relation to body composition and insulin concentration in patients with endogenous Cushing's syndrome compared to controls matched for body mass index.

Cushing's syndrome (CS) is associated with weight gain and visceral obesity. We examined the relationship between regional fat distribution and serum levels of leptin, cortisol and insulin. Twenty-three consecutive patients with recently diagnosed CS (18 with pituitary adenoma, 5 with adrenal tumor), where compared to obese controls, matched for age, sex and Body Mass Index (BMI).

Ceftriaxone and amikacin versus ceftazidime and amikacin in febrile granulocytopenia.

The efficacy and safety of the two antibiotic combinations, ceftazidime plus amikacin and ceftriaxone plus amikacin were compared in an open randomized trial. 100 episodes of neutropenia caused by malignant diseases and/or cytostatic drugs were evaluated in 66 males and 34 females with a mean age of 49.4 years.

[Amborum Special F and ASFO--2 glucocorticoid-containing herbal remedies].

Amborum Special F and ASFO are two names of a herbal remedy which is adulterated with the glucocorticoid betamethasone. Patients with asthma, rheumatic and chronic diseases import the drug direct from Burbank, California, USA. Its impressive antiasthmatic effect is reported in two patients.

[Simultaneous occurrence of hemophilia A and acute lymphatic leukemia].

In this paper the case of a man with haemophilia A is presented. At the age of 18 years an acute lymphatic leukaemia was observed. The case report demonstrates that even in the presence of a severe plasmatic coagulopathy an acute lymphatic leukaemia can be successfully treated with intensive chemotherapy, if the monitoring of the coagulation values and the substitution of antihaemophilic globulin and thrombocytes are guaranteed.

[Open tuberculosis with radiologically negative cavity findings].

Non-cavernous bacillary tuberculosis is observed with relatively increasing frequency nowadays. Most patients affected have very few or no symptoms, and radiographs usually show circumscribed lesions. The essential feature is the low infection risk due to the small number of bacilli excreted.

Aminopyrine N-demethylation by rats with liver cirrhosis. Evidence for the intact cell hypothesis. A morphometric-functional study.

The intact cell hypothesis states that a reduced number of intrinsically normal hepatocytes, together with hemodynamic alterations, explains decreased drug metabolism in cirrhosis. We explored this hypothesis by comparing results of the aminopyrine breath test with in vitro measurements of aminopyrine N-demethylation and morphometrically determined liver cell volume in a rat model of cirrhosis. Aminopyrine N-demethylation in vivo (ABT-k) was 0.

Ameloblastic fibroma and its sarcomatous transformation.

A case of ameloblastic fibroma, and one of its more aggressive variety, the ameloblastic "fibrosarcoma", are presented. The clinical and morphologic differences are discussed. In our opinion, ameloblastic "fibrosarcoma" is a semimalignant tumor.