Publications by authors named "Scarlett Brown"
Article Synopsis
- Extensive DNA methylation changes linked to human obesity have been identified, with significant associations in adipose tissue samples.
- The study connects obesity-related methylation variations to changes in gene expression, affecting over 500 target genes and suggesting interactions with transcription factors.
- Through various techniques, including Mendelian Randomisation, researchers infer that these methylation changes have causal effects on obesity and its metabolic issues, highlighting their role in adipocyte function.
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