Background: Due to the current importance of dental whitening, multiple studies have been carried out in order to achieve an efficient, effective, and innocuous procedure. This study aimed to compare the effectiveness and sensitivity of in-office dental bleaching with one versus two applications of 6% hydrogen peroxide (HP) gel with nitrogen titanium dioxide (TiO) nanoparticles activated by LED/Laser lamp in a single-session.
Methods: This RCT with a split-mouth design was performed in twenty-seven volunteers.