Nurse practitioner and physician associate mentorship: Improving retention and employment experiences.

Background: Clinician turnover is costly for health care organizations.

Local Problem: A retention strategy for newly hired nurse practitioners (NPs) and physician associates (PAs) was needed at our organization.

Methods: A quality improvement project was conducted to determine whether a mentorship program could improve retention and employment experiences of newly hired NPs and PAs.

Collection and sharing of health information in mental health and related systems in Australia: perspectives of people who access mental health services.

Background: Information sharing and information privacy are important issues in mental health services. Yet the perspectives of Australians who access mental health services about these issues are poorly understood. This article addresses the research question: What are the concerns of people who use mental health services about the collection and use of their health information in mental health and related systems in Australia?

Methods: Participants were 16 people who had accessed mental health services and were involved in a series of co-design workshops as part of a larger study.

Large-scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity.

Introduction: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease, yet our comprehension predominantly relies on studies within non-Hispanic White (NHW) populations. Here we provide an extensive survey of the proteomic landscape of AD across diverse racial/ethnic groups.

Methods: Two cortical regions, from multiple centers, were harmonized by uniform neuropathological diagnosis.

A Review of Digital Interventions as Secondary Prevention Measures to Combat Online Child Sexual Abuse Perpetration.

Interventions implemented in the digital space play an important role in the response to global concerns about the prevalence of online child sexual abuse. Digital detection software (e.g.

Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations.

Introduction: Multi-omics studies in Alzheimer's disease (AD) revealed many potential disease pathways and therapeutic targets. Despite their promise of precision medicine, these studies lacked Black Americans (BA) and Latin Americans (LA), who are disproportionately affected by AD.

Methods: To bridge this gap, Accelerating Medicines Partnership in Alzheimer's Disease (AMP-AD) expanded brain multi-omics profiling to multi-ethnic donors.

Over a decade of UAV incidents: A human factors analysis of causal factors.

This analysis examined systemic causes of Uncrewed Air Vehicle (UAV) accidents identifying operator, environmental, supervisory, and organisational factors through the use of the Human Factors Analysis and Classification System (HFACS). HFACS is a system-based analysis method for investigating the causal factors associated with accidents and incidents and has previously been used to reliably and systematically identify active and latent failures associated with both military and general aviation accidents. Whilst HFACS has previously been applied to UAV accidents, the last known application was conducted in 2014.

Measurement properties of the Thai translation of the Recovery Assessment Scale - Domains and Stages (RAS-DS) and comparison of recovery experiences between Thai and Australian consumers living with serious mental illness.

Personal recovery, a western conceptualisation that focuses on hope and living meaningful lives of choice rather than focusing on symptom reduction, is a more recent concept in many Asian countries including Thailand. One way to promote recovery-oriented service delivery is to use outcome measures that capture self-reported personal recovery. This study aimed to evaluate a Thai translation of a self-report measure of mental health recovery, the Recovery Assessment Scale - Domains and Stages (RAS-DS).

Enabling cyber resilient shipping through maritime security operation center adoption: A human factors perspective.

The increased adoption of digital systems in the maritime domain has led to concerns about cyber resilience, especially in the wake of increasingly disruptive cyber-attacks. This has seen vessel operators increasingly adopt Maritime Security Operation Centers (M-SOCs), an action in line with one of the cyber resilience engineering techniques known as adaptive response, whose purpose is to optimize the ability to respond promptly to attacks. This research sought to investigate the domain-specific human factors that influence the adaptive response capabilities of M-SOC analysts to vessel cyber threats.

Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations.

Introduction: Multi-omics studies in Alzheimer's disease (AD) revealed many potential disease pathways and therapeutic targets. Despite their promise of precision medicine, these studies lacked African Americans (AA) and Latin Americans (LA), who are disproportionately affected by AD.

Methods: To bridge this gap, Accelerating Medicines Partnership in AD (AMP-AD) expanded brain multi-omics profiling to multi-ethnic donors.

Metformin and feeding increase levels of the appetite-suppressing metabolite Lac-Phe in humans.

Metformin, a widely used first-line treatment for type 2 diabetes (T2D), is known to reduce blood glucose levels and suppress appetite. Here we report a significant elevation of the appetite-suppressing metabolite N-lactoyl phenylalanine (Lac-Phe) in the blood of individuals treated with metformin across seven observational and interventional studies. Furthermore, Lac-Phe levels were found to rise in response to acute metformin administration and post-prandially in patients with T2D or in metabolically healthy volunteers.

Feasibility of Recovery Assessment Scale - Domains and Stages (RAS-DS) for everyday mental health practice.

Introduction: Routine use of self-rated measures of mental health recovery can support recovery-oriented practice. However, to be widely adopted, outcome measures must be feasible. This study examined the feasibility of Recovery Assessment Scale - Domains and Stages (RAS-DS) from the perspectives of mental health workers.

Mood states and academic performance in the objective structured clinical examination. The mediating effect of self-efficacy.

Background: The role of self-efficacy on academic outcomes in clinical simulation evaluations is well-known. However, no previous studies have reported the mediating effect of self-efficacy in the link between mood state and academic performance in the Objective Structured Clinical Examination (OSCE).

Objectives: This study explores the following aims: i) to determine the effects of mood states on academic performance; ii) to assess the effect of mood states on self-efficacy; and iii) to analyze whether self-efficacy mediates the relationship between mood state and academic performance in the OSCE.

Phylogenomics of the Ecdysteroid Kinase-like (EcKL) Gene Family in Insects Highlights Roles in Both Steroid Hormone Metabolism and Detoxification.

The evolutionary dynamics of large gene families can offer important insights into the functions of their individual members. While the ecdysteroid kinase-like (EcKL) gene family has previously been linked to the metabolism of both steroid molting hormones and xenobiotic toxins, the functions of nearly all EcKL genes are unknown, and there is little information on their evolution across all insects. Here, we perform comprehensive phylogenetic analyses on a manually annotated set of EcKL genes from 140 insect genomes, revealing the gene family is comprised of at least 13 subfamilies that differ in retention and stability.

Using Natural Language Processing to Predict Risk in Electronic Health Records.

Clinical narratives recording behaviours and emotions of patients are available from EHRs in a forensic psychiatric centre located in Tasmania. This rich data has not been used in risk prediction. Prior work demonstrates natural language processing can be used to identify patient symptoms in these free-text records and can then be used to predict risk.

Bridging the Gap: Enhancing Maritime Vessel Cyber Resilience through Security Operation Centers.

Increasingly disruptive cyber-attacks in the maritime domain have led to more efforts being focused on enhancing cyber resilience. From a regulatory perspective, there is a requirement that maritime stakeholders implement measures that would enable the timely detection of cyber events, leading to the adoption of Maritime Security Operation Centers (M-SOCs). At the same time, Remote Operation Centers (ROCs) are also being discussed to enable increased adoption of highly automated and autonomous technologies, which could further impact the attack surface of vessels.

Bilateral rTMS Shows No Advantage in Depression nor in Comorbid Depression and Anxiety: A Naturalistic Study.

The objective was to determine if adding low-frequency right-sided rTMS treatment to the standard high-frequency left-sided treatment (LUL), referred to as sequential bilateral treatment (SBT), confers additional benefit for depression or anxiety outcomes. A retrospective chart review from January 2015 through December 2018 yielded 275 patients, all of whom were treated with a figure-8 coil for a major depressive episode. Their protocol was either LUL or SBL.

Understanding the impostor phenomenon in graduate nursing students.

Intuitively, nurse educators know that graduate students in both master's and doctoral programs question their ability to succeed. The impostor phenomenon (IP) is an internalized sense of inadequacy and fear of being seen as a fraud in the presence of external indicators of authentic achievement, and experienced by high achieving, successful individuals. Fifty-three percent (49/93) of graduate students completed the CIPS survey, and 11 master's (regular streams & nurse practitioner) and two doctoral students participated in focus group interviews.

Supporting self-determination in mental health recovery: Strategies employed by occupational therapists.

Introduction: Self-determination is a core component of mental health recovery and a predictor of positive outcomes. The literature calls for occupational therapists to lead practice change to greater recovery-orientation, including facilitating people's self-determination. However, systemic challenges thwart translation of policy into practice and therapists report a lack of confidence in implementing recovery-oriented principles.

Cross-Cultural Adaptation and Psychometric Evaluation of Condom Use Self-Efficacy Scale in Chilean College Students.

Limited culturally relevant condom self-efficacy measures have been adapted for use with Chilean college students. This study aims to culturally adapt and measure the psychometric properties of the Condom Use Self-Efficacy Scale (CUSES) by use in college students in Chile. This cross-sectional study was carried out in six stages: (a) authorization from original authors, (b) translation, (c) back translation, (d) analysis of equivalences, (e) content analysis, and (f) exploratory factor analysis and reliability assessment.

Staff perceptions of factors affecting the use of RAS-DS to support collaborative mental health practice.

Background: The Recovery Assessment Scale: Domains and Stages (RAS-DS) was designed to be both a recovery outcome measure and a tool to enhance service-user control over their recovery journey. While extensively and globally used in mental health services for the former purpose, routine use for the latter purpose is yet to be realised. The aim of this study was to identify barriers, facilitators and additional supports needed for RAS-DS to be used to support service user participation, goal setting and recovery action planning.