Production of recombinant lumpy skin disease virus A27L and L1R proteins for application in diagnostics and vaccine development.

Vaccination using live attenuated vaccines (LAVs) is considered the most effective method for control of lumpy skin disease (LSD). However, this method is limited by safety concerns, with reports of adverse reactions following vaccination. This study evaluates A27L and L1R which are essential proteins for virus attachment and membrane fusion as recombinant sub-unit vaccines against LSD.

Caseinolytic Proteins (Clp) in the Genus : Special Focus on ClpK.

Caseinolytic proteins (Clp), which are present in both prokaryotes and eukaryotes, play a major role in cell protein quality control and survival of bacteria in harsh environmental conditions. Recently, a member of this protein family, ClpK was identified in a pathogenic strain of which was responsible for nosocomial infections. ClpK is linked to the thermal stress survival of this pathogen.