Publications by authors named "Sayyed Reza Adhamdoust"
Efficient synthesis of stable phosphonate ylides and phosphonate esters: reaction between activated acetylenes and triphenylphosphite in the presence of sulfonamide and heterocyclic NH-acids.
Faramarz Rostami Charati Malek Taher Maghsoodlou Sayyed Mostafa Habibi-Khorassani Nourallah Hazeri Ali Ebrahimi Sayyed Reza Adhamdoust
Comb Chem High Throughput Screen
January 2011
Article Synopsis
- A one-pot reaction method was developed to efficiently synthesize stable phosphonate ylides and esters using activated acetylenes and triphenylphosphite, along with sulfonamides and NH-acids.
- Characterization of the resulting ylides and phosphonate esters was conducted through single X-ray diffraction and NMR studies.
- Dynamic NMR studies on a phosphonate ylide enabled the determination of the free energy barrier for the isomerization between the (E) and (Z) geometrical forms.