Evaluating the Influence of Clinical Data on Inter-Observer Variability in Optic Disc Analysis for AI-Assisted Glaucoma Screening.

Purpose: This study aims to evaluate the inter-observer variability in assessing the optic disc in fundus photographs and its implications for establishing ground truth in AI research.

Methods: Seventy subjects were screened during a screening campaign. Fundus photographs were classified into normal (NL) or abnormal (GS: glaucoma and glaucoma suspects) by two masked glaucoma specialists.

Advanced Analysis of OCT/OCTA Images for Accurately Differentiating Between Glaucoma and Healthy Eyes Using Deep Learning Techniques.

Purpose: To evaluate the discriminative power of optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) images, identifying the best image combination for differentiating glaucoma from healthy eyes using deep learning (DL) with a convolutional neural network (CNN).

Methods: This cross-sectional study included 157 subjects contributing 1,106 eye scans. We used en-face images of the superficial and choroid layers for OCTA-based vessel density and OCT-based structural thickness of the macula (M) and optic disc (D).

Permanent Severe Visual Field Defect Following Pre-eclampsia and Multiple Ophthalmological Pathologies: A Case Report.

This clinical report discusses the interplay of various pathologies that may present similar clinical manifestations, with uncertainty about the distinct impact of each one of them. The patient is a 43-year-old young Asian female with no known medical conditions. She was 33 weeks pregnant when she was admitted for an urgent c-section because of preeclampsia with HELLP syndrome.

Unmasking an unusual presentation of Hodgkin's lymphoma masquerading as ocular inflammation: a case report.

Background: Hodgkin's lymphoma (HL) is an extremely rare cause of ocular inflammation that is usually not considered in the typical workup of uveitis and other eye diseases. A few cases of ocular inflammation were reported previously showcasing HL with absence of typical symptoms of HL at presentation. Acknowledging the potential ocular inflammation associated with HL can prompt ophthalmologists to broaden their diagnostic approach and collaborate with internal medicine departments to investigate this rare yet significant etiology.

Intermediary inflammatory reaction after micropulse cyclophotocoagulation diode therapy: a case report.

Introduction: Of the many types of laser cyclophotocoagulation procedures, micropulse cyclophotocoagulation diode is praised as a noninvasive, safe, and effective procedure with few complications. In this case report, we describe a rare complication that, to the best of our knowledge, has not been previously reported.

Case Report: We report on the case of a 66-year-old African man with a history of end-stage primary open-angle glaucoma.

Real-life experience of micropulse transscleral cyclophotocoagulation (MP-TSCPC) in advanced and uncontrolled cases of several glaucoma types: a multicentric retrospective study.

Purpose: In this retrospective case series multicentric study, we assessed the efficiency and safety of micropulse transscleral cyclophotocoagulation (MP-TSCPC) among several types of advanced uncontrolled glaucoma cases. This study was intended to be a real-life study.

Methods: We treated 55 eyes with the Iridex Cyclo G6 device with the MP3 handpiece (IRIDEX Laser Systems) using a standardized protocol.

Accurate prediction of glaucoma from colour fundus images with a convolutional neural network that relies on active and transfer learning.

Purpose: To assess the use of deep learning (DL) for computer-assisted glaucoma identification, and the impact of training using images selected by an active learning strategy, which minimizes labelling cost. Additionally, this study focuses on the explainability of the glaucoma classifier.

Methods: This original investigation pooled 8433 retrospectively collected and anonymized colour optic disc-centred fundus images, in order to develop a deep learning-based classifier for glaucoma diagnosis.

Systemic exposure to intracameral vs topical mydriatic agents: in cataract surgery.

Objective: The objective of this study was to compare systemic exposure to tropicamide/phenylephrine following intracameral or topical administration before cataract surgery.

Patients And Methods: Mydriatics exposure was calculated in patients randomized to intracameral fixed combination of mydriatics and anesthetic ([ICMA]: tropicamide 0.02%, phenylephrine 0.

Biomechanical parameters of the cornea measured with the Ocular Response Analyzer in normal eyes.

Background: To evaluate the relationships between Reichert Ocular Response Analyzer (ORA) parameters corneal hysteresis (CH) and corneal response factor (CRF) and ocular dimensions, age and intraocular pressure.

Methods: Two hundred and twelve eyes of 212 participants with no ocular pathology had CH and CRF measured with the ORA. Intraocular pressure (IOP) was measured with the Dynamic Contour tonometer and central corneal thickness (CCT) was also evaluated.

Comparison of the corneal biomechanical properties with the Ocular Response Analyzer® (ORA) in African and Caucasian normal subjects and patients with glaucoma.

Purpose: To compare corneal hysteresis (CH) and corneal resistance factor (CRF) measured with the Ocular Response Analyzer(®) tonometer (ORA) between (i) African normals and treated primary open-angle glaucoma (POAG) patients and (ii) between normals and treated POAG Caucasians. To analyse the correlation of CH and CRF with visual field (VF) defects in the two groups.

Methods: This comparative study included 59 African (29 (POAG), 30 normals) and 55 Caucasians (30 POAG and 25 normals) subjects.

Physiological diurnal variability and characteristics of the ocular pulse amplitude (OPA) with the dynamic contour tonometer (DCT-Pascal).

Purpose: The Pascal dynamic contour tonometer (DCT) allows measurement of intraocular pressure (IOP) independently of corneal properties. It records, simultaneously, haemodynamic IOP fluctuations and the difference between the systolic and the diastolic IOP corresponding to the ocular pulse amplitude (OPA). The OPA indirectly reflects choroidal perfusion and could be considered as an independent risk factor in glaucoma.

Anterior segment imaging using optical coherence tomography and ultrasound biomicroscopy in secondary pigmentary glaucoma associated with in-the-bag intraocular lens.

A 43-year-old man with high myopia developed unilateral pigmentary glaucoma with recurrent episodes of painless blurred vision in the left eye following uneventful phacoemulsification. Bilateral cataract surgery was performed with capsular bag implantation of a +4.00 diopter AcrySof MA60 intraocular lens (IOL) (Alcon Laboratories) followed by a neodymium:YAG laser capsulotomy.