Publications by authors named "Sayeh Jalali"
Background: Erectile dysfunction (ED) has been linked to insulin resistance (IR), with various surrogate indices being used to assess this association. This systematic review and meta-analysis aimed to evaluate the relationship between IR indices and the incidence and severity of ED.
Methods: A comprehensive search across PubMed, Embase, Web of Science, and Scopus was carried out.
Article Synopsis
- Early-life exposure to famine is linked to a higher risk of osteoporosis, fractures, and decreased bone mineral density (BMD) in later life, indicating significant long-term health impacts.
- A systematic review and meta-analysis of 10 studies revealed that individuals exposed to famine during critical developmental periods had greater odds of developing osteoporosis (2.12 times) and experiencing fractures (1.58 times) compared to those not exposed.
- Key findings suggest that exposure during fetal and childhood stages has particularly strong associations with poor bone health outcomes, highlighting the importance of early nutrition and health interventions.
Highly active antiretroviral therapy (HAART) can suppress HIV replication to undetectable levels in plasma, but it is unlikely to eradicate cellular reservoirs of virus. Immunotherapies that are cytolytic may be useful adjuncts to drug therapies that target HIV replication. We have generated HIV-specific CD4(+) and CD8(+) T cells bearing a chimeric T-cell receptor (CD4zeta) composed of the extracellular and transmembrane domain of human CD4 (which binds HIVgp120) linked to the intracellular-zeta signaling chain of the CD3 T-cell receptor.
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