Does hepatitis E viral load and genotypes influence the final outcome of acute liver failure during pregnancy?

Background: Hepatitis E is a major health problem in developing countries including India. The incidence and mortality rate in pregnant women with fulminant hepatic failure (FHF) due to hepatitis E virus (HEV) has been reported to be significantly higher, specifically in Asian women. Pregnancy is usually associated with an altered status of sex steroid hormones and immunity.

Lindane-induced immunological alterations in human poisoning cases.

Objectives: Evaluation of immunological alterations in the blood of human lindane poisoning cases.

Design And Methods: Serum IgG, IgM, IgA, IgE, IL-2, IL-4, TNF-alpha, and IFN-gamma levels were measured using immunoassay in 20 human cases of lindane poisoning. The presence of lindane in blood was confirmed by HPLC.