Publications by authors named "Sayed Mustafa Albushra"
Infect Drug Resist
January 2024
Article Synopsis
- The study investigated the prevalence of mutations associated with chloroquine resistance in malaria-causing *Plasmodium falciparum* strains in Nyala, Sudan, following the shift to using artesunate and sulfadoxine/pyrimethamine as first-line treatments in 2004.
- Using techniques like polymerase chain reaction (PCR) and gel electrophoresis, researchers analyzed DNA from 75 isolates and found that significant frequencies of both the K76T and N86Y mutations were present, indicating ongoing chloroquine resistance.
- Results showed that K76T mutations were found in 65.3% of isolates, and N86Y mutations in 45.3%, suggesting that chloroquine resistance markers continue
