Publications by authors named "Sayed A Mahmud"

Irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD) are prevalent gastrointestinal disorders with significant global prevalence. Conventional treatments often have adverse effects, prompting interest in probiotics as alternative therapies. This systematic review assesses the efficacy of probiotics in managing symptoms and improving outcomes in adult patients with IBS and IBD.

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Coronary artery disease (CAD) is a significant health concern that has affected approximately 110 million people worldwide. CAD is defined as persistent narrowing of the coronary arteries as a result of atherosclerotic plaque build-up. Acute coronary syndrome (ACS), which encompasses ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI), and unstable angina, often results from plaque ruptures.

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Article Synopsis
  • Adults with inflammatory bowel disease (IBD) face a decline in quality of life, and exercise may help improve their management and overall well-being.
  • A systematic review analyzed 12 high-quality studies and found that exercise interventions positively affected cardiorespiratory fitness, disease activity, quality of life, and mental health in IBD patients.
  • While the evidence supports exercise as a beneficial treatment, more research is needed to develop personalized exercise programs and understand how exercise benefits IBD management.
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Type 2 diabetes mellitus (T2DM) is a major global health concern with a strong association with increased cardiovascular morbidity and mortality. The prevalence of heart failure is significantly higher in the T2DM population compared to non-diabetic individuals. Sodium-glucose cotransporter-2 (SGLT-2) inhibitors have emerged as a promising therapeutic class for managing T2DM, with potential cardioprotective effects.

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