Primary immunodeficiencies : Report of 33 Pediatric Tunisian cases.

Background Primary immunodeficiencies (PID) are a group of heterogeneous and relatively rare diseases. Aim to determine the clinical characteristics, outcome and genetic data of primary immunodeficiencies in pediatrics patients. Methods A retrospective, descriptive and multicentered study, enrolling 33 children presenting a PID in Tunis, during a period of 22 years (1991-2012).

[Clinical and etiological features of primary adrenal insufficiencies in children].

Background: The chronic primary adrenal insufficiency or Addison's disease is uncommon in children and belongs generally to a complex syndrome.

Aim: Study of the clinical and aetiological features of primary adrenal insufficiencies in children.

Methods: In a retrospective study, we reviewed clinical and diagnostic data of all cases of Addison's disease admitted within a period of 15 years (from january 1991 to December 2006), in a department of paediatrics.

[Cholestasis in infants: a study of the Children's Hospital of Tunisia].

Background: Cholestasis in infant constitutes an heterogeneous group of disease; diagnosis and management are often difficult. THE AIM of the study is to describe clinical, paraclinical characteristics and outcome of infants hospitalized for cholestasis in children's Hospital of Tunis.

Methods: A retrospective study of 94 infants with cholestasis was conducted.

[Hyperlipidaemia associated to inaugurated diabetic ketoacidosis].

Severe hyperlipidaemia in presenting diabetic ketoacidosis was rarely reported in child. We report the case of a three-year-old girl with presenting diabetic ketoacidosis. Family history was negative for hyperlipidaemia.