Publications by authors named "Savithramma N"

Article Synopsis
  • A study analyzed 2826 phytochemicals for their potential toxicity and ability to interfere with hormone receptors, focusing on mutagenicity, carcinogenicity, developmental toxicity, skin sensitization, and estrogen receptor-binding affinity.
  • The VEGA QSAR modeling package was used to predict toxicity effects and classify chemicals, with the results helping to identify significant clusters that may indicate potential health risks.
  • The developed QSAR models demonstrated strong predictive capabilities, offering a new method to assess the toxicity levels of phytochemicals and environmental pollutants, potentially enhancing human health protection.
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Aim: This study aims to isolate, characterize, and evaluate of anticancer polyphenols from different parts of .

Materials And Methods: The polyphenols were isolated by standard protocol and characterized using Fourier-transform infrared (FT-IR), High performance liquid chromatography - Photodiode array detector coupled with Electrospray ionization - mass spectrometry (MS/MS). The compounds were elucidated based on retention time and molecular ions () either by [M+H]/[M-H] with the comparison of standard phenols as well as ReSpect software tool.

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Article Synopsis
  • The study focused on documenting the traditional knowledge of medicinal plants used by the Yanadi tribe in Andhra Pradesh and validating their antimicrobial properties.
  • The researchers used a questionnaire to gather data on the plants, verifying their medicinal uses with Dr. Duke's Database and existing literature.
  • Results indicated that herbs were predominantly used, with most preparations being pastes for oral consumption; the study also found significant antimicrobial activity in selected plant extracts.
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Aim: In the present study, we report a cost-effective, eco-friendly, and an efficient alternative method for large scale production of silver nanoparticles (AgNPs) from Adansonia digitata fruit pulp extract. The study mainly focused on the synthesis, characterization, and antimicrobial properties of AgNPs.

Materials And Methods: Synthesis of AgNPs with the help of standard protocol and characterized by ultraviolet (UV)-vis spectrophotometry, Fourier transform infra-red (FTIR), X-ray diffractometer (XRD), atomic force microscopy (AFM), scanning electron microscopy (SEM) with EDAX, transmission electron microscopy (TEM) and explore their potential growth inhibitory effect on 07 bacterial and 05 fungal pathogens.

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Aim: Ethnomedicinal studies on medicinal plants used by Yanadi tribe of Chandragiri reserve forest area are documented during the period of 2014-2015. The study is mainly focused on medicinal importance of plants used by Yanadi tribe to treat various ailments.

Materials And Methods: The information collected on treated ailments, part used, preparation, combination, and addition of ingredients to prepare herbal medicines with the help of standard questionnaire.

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Today green synthesis of silver nanoparticles (SNPs) from plants is an utmost emerging filed in nanotechnology. In the present study, we have reported a green method for synthesis of SNPs from aqueous stem bark extract of Syzygium alternifolium, an endemic medicinal plant of South Eastern Ghats. These green-synthesised nanoparticles are characterised by colour change pattern, and the broad peak obtained at 448 nm with UV-Vis surface plasmon resonance studies confirm that the synthesised nanoparticles are SNPs.

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Talinum cuneifolium (Vahl.) Willd. an erect shrub with subterranian tuber (Portulacaceae) is endowed with wide range of pharmacological activities.

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Tribal and non-tribal inhabitants of Andhra Pradesh used nearly 80 medicinal plants for treating asthma. The tribal people have a strong faith and belief in the traditional health care system, through herbal treatment. Plant species are generally used along with other materials and plant products in different combinations to effective cure.

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