Publications by authors named "Savitha Kanakpur"

Purpose: To assess the outcome and response of transcutaneous retrobulbar injection of amphotericin B (TRAMB) in post-coronavirus disease of 2019 (COVID-19) rhino-orbito-cerebral mucormycosis (ROCM) and to establish a scoring system in guiding treatment modalities.

Methods: An interventional, prospective study was done on 82 eyes of post-COVID-19 ROCM from May 2021 to July 2021. A comprehensive multi-departmental evaluation along with detailed ophthalmic examination, laboratory investigations, and radiological examination was done.

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Article Synopsis
  • The study focused on COVID-19-associated rhino-orbital-cerebral mucormycosis (ROCM) in India, examining patient demographics, risk factors, symptoms, and management outcomes during the pandemic's second wave.
  • Key findings revealed that 78% of patients had diabetes and a majority required oxygen support; most cases showed ROCM symptoms within 10-15 days post-COVID diagnosis.
  • Final outcomes indicated a 14% mortality rate, significantly reduced through surgical interventions, highlighting the role of corticosteroids and diabetes as major contributors to ROCM development.
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COVID-19 is a respiratory virus, which has affected various organ systems as well. Here we report a neuro-ophthalmic presentation of pituitary apoplexy under the setting of COVID-19 infection in a middle-aged man who presented to ophthalmic emergency with sudden bilateral loss of vision along with a history of fever past 10 days. There was sluggishly reacting pupils and RT-PCR for COVID was positive.

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Keratosis follicularis (Darier's disease) is a rare (1 in 30,000-100,000) genetic autosomal-dominant predominantly dermatological disorder characterized by hyperkeratosis and acantholysis due to a defective calcium transport in the cells. Ocular findings, if present, are very rare in this condition. Here, we are reporting a case of keratosis follicularis (Darier's disease) with ocular manifestations that have not been reported so far to the best of our knowledge.

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