Structural and functional analysis of a novel galactose-binding lectin derived from MW769776.

A freshwater green microalgal strain was isolated and the lectin was identified in it by a strong hemagglutination activity (HA) assay. Characterization of the algal strain was found to be (MW769776). A single step affinity chromatographic technique was developed to purify lectin (CSL) using guar gum as the affinity matrix.

Detection of in umbilical cord blood of new-born and in subgingival plaque of pregnant participants with periodontal disease and its association with pregnancy outcomes: An observational study.

Background: Preterm low birth weight (PLBW) is one of the causes of infant mortality and morbidity. Most of the studies have indicated the periodontal-systemic interlink. The association of periodontal pathogen on pregnancy outcome still stands inconclusive.

Deacylation of Echinocandin B by Streptomyces species: a novel method for the production of Echinocandin B nucleus.

Anidulafungin, a new class of antifungal agent used for the treatment of chronic fungal infections, is derived from Echinocandin B nucleus, an intermediate metabolite of Echinocandin B produced by . The enzyme acylase plays a key role in the bioconversion of Echinocandin B to Echinocandin B nucleus. In the present study, a rapid screening method was used to select an actinomycete capable of producing Echinocandin B acylase.

Comparative Study on Whole Genome Sequences of Aspergillus terreus (Soil Fungus) and Diaporthe ampelina (Endophytic Fungus) with Reference to Lovastatin Production.

Lovastatin is a competitive inhibitor of the enzyme hydroxymethyl glutaryl coenzyme A reductase (HMGR) in cholesterol biosynthetic pathway and hence used in the treatment of hyperlipidemia. In a previous study, we report a tropical soil isolate, Aspergillus terreus (KM017963), which produces ample amount of lovastatin than its counterpart that are endophytic in origin. Bioinformatic analysis of whole genome sequence of A.

Wheat flour, an inexpensive medium for cultivation of coprophilous fungus .

, a coprophilous basidiomycetous fungus generally called as inky cap mushroom is used as a model organism to study the evolution of fruiting bodies in higher fungi. Herbivorous animal dung is a major source of , as it contains high carbon, nitrogen, and phosphorus elements. Due to the extensive application of in Genetics, Molecular Biology and Microbial Biotechnology it is necessary to explore a suitable inexpensive medium for its cultivation.

Purification of Lovastatin from Aspergillus terreus (KM017963) and Evaluation of its Anticancer and Antioxidant Properties.

Cervical cancer is the second most common malignancy in women worldwide and thus one of the leading causes of mortality in women. Lovastatin, a non polar, anticholesterol drug has previously been reported to exert antitumour activity in vitro. In the present study, lovastatin from Aspergillus terreus (KM017963) was purified by adsorption chromatography and evaluated for its anticancer and anti-oxidant properties with a human cervical cancer cell line (HeLa).

Complete Genome Sequence of Soil Fungus Aspergillus terreus (KM017963), a Potent Lovastatin Producer.

We report the complete genome of Aspergillus terreus (KM017963), a tropical soil isolate. The genome sequence is 29 Mb, with a G+C content of 51.12%.

Complete Genome Sequence of the Endophytic Fungus Diaporthe (Phomopsis) ampelina.

Diaporthe ampelina was isolated as an endophytic fungus from the root of Commiphora wightii, a medicinal plant collected from Dhanvantri Vana, Bangalore University, Bangalore, India. The whole genome is 59 Mb, contains a total of 905 scaffolds, and has a G+C content of 51.74%.

Arsenate resistant Penicillium coffeae: a potential fungus for soil bioremediation.

Bioremediation is an effective method for the treatment of major metal contaminated sites. Fungi were isolated from soil samples collected from different arsenate contaminated areas across India. An isolate, Penicillium coffeae, exhibited resistance to arsenate up to 500 mM.

Amylase production by endophytic fungi Cylindrocephalumsp. isolated from medicinal plant Alpinia calcarata (Haw.) Roscoe.

Amylases are among the most important enzymes used in modern biotechnology particularly in the process involving starch hydrolysis. Fungal amylase has large applications in food and pharmaceutical industries. Considering these facts, endophytic fungi isolated from the plant Alpinia calcarata (Haw.

Oral field cancerization: current evidence and future perspectives.

Introduction: Oral field cancerization implies that oral cancer does not arise as an isolated cellular phenomenon but rather as an anaplastic tendency involving many cells at once and results in the multifocal development of cancer at various rates within the entire field in response to a carcinogen especially tobacco. This concept has been frequently used to explain the occurrence of multiple primary cancers and recurrences following complete excision of oral cancer.

Discussion: This review deals in detail with the origin, principle, various theories used to explain this effect and molecular, genetic, as well as cytogenetic findings related to oral field cancerization.

An inducible, intracellular, alkalophilic lipase inAspergillus flavipes grown on triacylglycerols.

An intracellular lipase was induced inAspergillus flavipes grown on various triacylglycerols at pH 6.0 and at 30°C, with maximum activity with sunflower oil. The lipase had an optimum pH for activity of 8.