: unprecedented L-dopa content and its role in neurodegenerative and inflammatory conditions.

Unlabelled: Genus encompasses several plant species renowned for their utilization in traditional Ayurvedic medicine for the treatment of Parkinson's disease, chiefly due to their exceptionally high L-dopa content relative to other plants. However, limited information exists regarding , a newly identified species within the genus. This study unveils a remarkable L-dopa content of 174.

Plant and yeast consortium for efficient remediation of dyes and effluents: a biochemical and toxicological study.

Textile effluent carries a range of dyes that may be recalcitrant and resistant to biodegradation. A unique consortium of the Fimbristylis dichotoma and Saccharomyces cerevisiae is exploited for the biodegradation of an azo dye Rubine GFL and actual textile effluent. This consortium enhances the rate of biodegradation of Rubine GFL and actual textile effluent with an excellent rate of biodegradation of 92% for Rubine GFL and 68% for actual textile effluent when compared to the individual one within 96 h.

Molecular insights into plant-microbe interactions for sustainable remediation of contaminated environment.

The widespread distribution of organic and inorganic pollutants in water resources have increased due to rapid industrialization. Rhizospheric zone-associated bacteria along with endophytic bacteria show a significant role in remediation of various pollutants. Metaomics technologies are gaining an advantage over traditional methods because of their capability to obtain detailed information on exclusive microbial communities in rhizosphere of the plant including the unculturable microorganisms.

Thermoresponsive Pluronic based microgels for controlled release of curcumin against breast cancer cell line.

We developed here stimuli responsive curcumin loaded microgels based on Pluronic F-127. These microgels were prepared using coupling reaction between the amine modified Pluronic and EDTA. The microgel exhibited the affinity for hydrophobic drug, curcumin and showed pH as well as temperature-dependent release.

Synthesis and Evaluation of Cytotoxicity of Novel Coumarin Peptide Alcohol Derivatives.

Background: Coumarins are naturally occurring biologically active heterocyclic molecules endowed with a wide range of biological properties, including antibacterial, antifungal, and antitumor activities.

Objective: The present work was aimed to synthesize new coumarin-containing compounds and to investigate their cytotoxic activity.

Methods: Coumarin peptide and coumarin amino alcohols were prepared by treating epoxidecontaining coumarin derivatives with suitable aromatic amines and peptides in trifluoroethanol as a solvent at 50°C.

In vitro toxicological evaluation of ionic liquids and development of effective bioremediation process for their removal.

The present study deals with the cyto-genotoxicological impact of ionic liquids, 1-butyl-3-methylimidazolium bromide, trihexyl tetradecylphosphonium dicyanamide, 1-decyl-3-methylimidazolium tetrafluoroborate, benzyldimethyltetradecylammonium chloride, and 1-butyl-4-methylpyridinium chloride, on animal cells and their biodegradation. The long alkyl chain containing ionic liquids were found to be more toxic whereas benzene functional group in benzyldimethyltetradecylammonium chloride enhances its toxicity. Aerobic bacterial granules, a bacterial consortium, were developed that have promising ability to break down these organic pollutants.

Click chemistry based multicomponent approach in the synthesis of spirochromenocarbazole tethered 1,2,3-triazoles as potential anticancer agents.

A series of spirochromenocarbazole tethered 1,2,3-triazoles were synthesized via click chemistry based one-pot, five component reaction between N-propargyl isatins, malononitrile, 4-hydroxycarbazole, aralkyl halides and sodium azide using cellulose supported CuI nanoparticles (Cell-CuI NPs) as the heterogeneous catalyst. Antiproliferative activity of all the synthesized compounds was investigated against panel of cancer cell lines such as MCF-7, MDA-MB-231, HeLa, PANC-1, A-549, and THP-1. Many of the synthesized compounds exhibited good anti-proliferative activity against breast (MCF-7 and MDA-MB-231) and cervical (HeLa) cancer cells with IC values less than 10 μM.

Assessment of arsenic oxidation potential of Microvirga indica S-MI1b sp. nov. in heavy metal polluted environment.

Arsenic oxidizing α-proteobacterial strain Microvirga indica S-MI1b sp. nov. was isolated from metal industry soil and has the ability to oxidize 15 mM of arsenite [As(III)] completely in 39 h.

Microvirga indica sp. nov., an arsenite-oxidizing Alphaproteobacterium, isolated from metal industry waste soil.

A novel Gram-stain-negative bacterium, strain S-MI1bT, belonging to the genus Microvirga was isolated from a metal industry waste soil sample in Pirangut village, Pune District, Maharashtra, India. Cells were non-spore-forming, small rod-shapes, motile and strictly aerobic with light-pink colonies. The strain grew in 0-7.

Evaluation of risk assessment of new industrial pollutant, ionic liquids on environmental living systems.

Ionic liquids (ILs) are much known for their promising alternative for volatile solvents in industries and gained popularity as a greener solvent, however industrial effluent discharge containing ILs are also increasing. There is a scarcity of information on the toxicity of ILs; the present study will explore different facts about their harmfulness. The toxic effects of five different ILs: [CMIM]Br, [HxPC]N(CN), [CMIM]BF, [BTDA]Cl and [CMPY]Cl were analysed on bacteria, fungi, plant and animal cells.

New record of a bloom forming, genotoxic strain Nodularia strain (KT447209) from Andaman and Nicobar Islands, India.

Cyanobacteria blooms in marine waters are limited to only a few taxa; with the genus Nodularia (Nostocales) being one among the most commonly observed and widely studied species. A bloom of Nodularia sp. was observed across a vast area along the coast of the Andaman and Nicobar Islands.

Simultaneous decolorization of reactive Orange M2R dye and reduction of chromate by Lysinibacillus sp. KMK-A.

Azo dyes constitute the largest and diverse group of dyes, widely used in number of industries that are contributing toward organic and inorganic load of effluent treatment. In the present study, Lysinibacillus sp. KMK-A was able to effectively decolorize Orange M2R dye up to 2000 mg l(-1) (Vmax of 19.