Utility of RNTCP (NTEP) guidelines in microbiological confirmation of pediatric tuberculosis.

Objective: To estimate the proportion of microbiologically confirmed disease among children diagnosed with tuberculosis using RNTCP guidelines.

Materials And Methods: Retrospective chart review of a cohort of 151 children (aged between 1 month and 18 years) diagnosed with Tuberculosis between December 2016 and June 2020 at a pediatric department of a tertiary care hospital. We collected information on AFB (Acid Fast Bacillus) smear and Cartridge Based Nucleic Acid Amplification Test (CB NAAT) results.

Revised Antituberculosis Drug Doses and Hepatotoxicity in HIV Negative Children.

Objectives: To compare the incidence of anti tuberculosis drug-induced hepatotoxicity (ATDH) with those on old vs. revised WHO doses in human immunodeficiency virus (HIV) negative children. The secondary objective was to determine the overall incidence of hepatitis in children on Anti tubercular treatment (ATT) and isoniazid prophylactic therapy (IPT).