Publications by authors named "Savio D Rodrigues"
Rhizogenic strains comprise biotrophic pathogens that cause hairy root disease (HRD) on hydroponically grown and crops, besides being widely explored agents for the creation of hairy root cultures for the sustainable production of plant-specialized metabolites. Hairy root formation is mediated through the expression of genes encoded on the T-DNA of the root-inducing (Ri) plasmid, of which several, including (), play a major role in hairy root development. Despite decades of research, the exact molecular function of the proteins encoded by the genes remains enigmatic.
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- The text discusses the role of certain plant pathogens, specifically spp., in causing diseases like crown gall and hairy root, and highlights their utility in plant genetic engineering due to their ability to transfer DNA to plant cells.* ! -
- It introduces a new method using CRISPR-mediated base editing to efficiently create targeted mutations in the genomes of specific strains, which has been a challenge due to obsolete laboratory strains and slow mutation processes.* ! -
- The study demonstrates successful mutations in the EHA105 strain, revealing the significance of specific genes for root development while also revealing off-target effects, paving the way for enhanced methods in plant transformation and genetic editing.* !