Publications by authors named "Saverio Gabrielli"

Background And Aims: Although rectal cancer is predominantly a disease of older patients, current guidelines do not incorporate optimal treatment recommendations for the elderly and address only partially the associated specific challenges encountered in this population. This results in a wide variation and disparity in delivering a standard of care to this subset of patients. As the burden of rectal cancer in the elderly population continues to increase, it is crucial to assess whether current recommendations on treatment strategies for the general population can be adopted for the older adults, with the same beneficial oncological and functional outcomes.

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The epidemiology and the outcomes of acute appendicitis in elderly patients are very different from the younger population. Elderly patients with acute appendicitis showed higher mortality, higher perforation rate, lower diagnostic accuracy, longer delay from symptoms onset and admission, higher postoperative complication rate and higher risk of colonic and appendiceal cancer. The aim of the present work was to investigate age-related factors that could influence a different approach, compared to the 2016 WSES Jerusalem guidelines on general population, in terms of diagnosis and management of elderly patient with acute appendicitis.

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Article Synopsis
  • - Gallstone disease is prevalent, affecting 20 million people in the U.S., with higher incidence in women and older adults, highlighting a growing health concern as the elderly population increases.
  • - The guidelines from a consensus conference aimed to address the treatment of acute calculous cholecystitis (ACC) specifically in elderly patients, noting differences from the general population and evaluating study quality.
  • - Surgical decisions for elderly patients with ACC are complex; while laparoscopic cholecystectomy is recommended, the use of frailty and risk scores can improve clinical judgments, indicating that age alone shouldn't disqualify patients from surgery.
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