Publications by authors named "Saurav Shankar"

Flexible technology in sensors have received much attention in monitoring of human health through various physiological indicators. Thus, it drawn a lot of interest in the development of flexible substrate for the diagnosis of various diseases via analysis of analytes. Present work focusses on the development of ecofriendly, portable, flexible, conducting thread (Th) and used as smart substrate for fabrication of biosensor towards ultrasensitive detection of the lung cancer biomarker (cytoskeleton-associated protein 4; CKAP4).

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Article Synopsis
  • Researchers developed an eco-friendly, flexible cotton thread biosensor to detect the swine flu biomarker serum amyloid A (SAA) with high sensitivity.
  • The cotton thread was coated with a conductive polymer, PEDOT:PSS, and enhanced with nanodot zirconium trisulfide (nZrS) to improve its electrochemical properties.
  • The biosensor exhibited excellent sensitivity and a low detection limit, with validations showing it accurately detects SAA in serum samples compared to standard tests.
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Lung cancer is the leading cause of cancer deaths globally; 1 in 16 people are diagnosed with lung cancer in their lifetime. Microtubules, a critical cytoskeletal assembly, have an essential role in cell division. Interference with the microtubule assembly leads to genetic instability during mitosis and cancer cell death.

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