Reindeer bone extract can heal the critical-size rat femur defect.

Bone extract from reindeer induces new ectopic bone formation (BF) in muscle pouches, but its feasibility in experimental bone lesions has not been evaluated. We investigated the effects of implants, containing 2, 5, 15, 20 or 50 mg of reindeer bone extract in a collagen carrier, on the healing of 8-mm femur defects in 78 rats. We used 30 µg of recombinant human bone morphogenetic protein-2 (rhBMP-2) in a collagen carrier, collagen and untreated defects as controls.

Bioglass as a carrier for reindeer bone protein extract in the healing of rat femur defect.

Bioactive glasses have been developed as scaffolds for bone tissue engineering but combination with reindeer bone protein extract has not been evaluated. We investigated the effects of bone protein extract implants (5-40 mg dosages) with bioglass (BG) carrier on the healing of rat femur defects. Bioglass implants and untreated defects served as controls.

Treatment of congenital pseudarthrosis of the tibia with native bovine BMP: a case report.

Bone morphogenetic proteins (BMP) have been shown to induce bone formation and union in long bone defects and nonunions. We report a case of congenital pseudarthrosis of the tibia treated with a composite implant consisting of a biocoral frame, collagen carrier, and native bovine BMP extract. A six-year-old boy had persisting congenital proximal tibial pseudarthrosis despite six prior operations.

Intraosseous schwannoma of the middle phalanx.

Intraosseous schwannoma is an extremely rare, benign neoplasm. Only a few cases involving the bones of the hand have been reported, and none of these cases has involved middle phalanx. We present a case of intraosseous schwannoma of the middle phalanx of the right ring finger.

Successful treatment of scaphoid fractures and nonunions using bioabsorbable screws: report of six cases.

Purpose: A variety of implants have been used for the fixation of scaphoid fractures, but we have found no reports on bioabsorbable screws used for this purpose. We report 6 cases of scaphoid fractures treated with bioabsorbable screws.

Methods: Six patients with scaphoid waist region fractures (3) and nonunions (3) treated using bioabsorbable self-reinforced poly-L-lactide screws.

Composite implant of native bovine bone morphogenetic protein (BMP), collagen carrier and biocoral in the treatment of resistant ulnar nonunions: report of five preliminary cases.

Introduction: Bone morphogenetic protein (BMP) has been shown to induce bone formation and union in long bone defects and nonunions. There are, however, no previous reports of BMP being used for ulnar nonunions. We report on five cases of resistant ulnar nonunions treated with a composite implant consisting of a biocoral frame, collagen carrier, and bovine BMP.

Biocompatibility and strength properties of nitinol shape memory alloy suture in rabbit tendon.

Nitinol (NiTi) is a promising new tendon suture material with good strength, easy handling and good super-elastic properties. NiTi sutures were implanted for biocompatibility testing into the right medial gastrocnemius tendon in 15 rabbits for 2, 6 and 12 weeks. Additional sutures were implanted in subcutaneous tissue for strength measurements in order to determine the effect of implantation on strength properties of NiTi suture material.

Effect of porosity on the osteointegration and bone ingrowth of a weight-bearing nickel-titanium bone graft substitute.

Porous nickel-titanium (NiTi) alloy is a promising new material for a bone graft substitute with good strength properties and an elastic modulus closer to that of bone than any other metallic material. The purpose of this study was to evaluate the effect of porosity on the osteointegration of NiTi implants in rat bone. The porosities (average void volume) and the mean pore size (MPS) were 66.

Bone modeling controlled by a nickel-titanium shape memory alloy intramedullary nail.

Nitinol (NiTi) shape memory metal alloy makes it possible to prepare functional implants that apply a continuous bending force to the bone. The purpose of this study was to find out if bone modeling can be controlled with a functional intramedullary NiTi nail. Pre-shaped intramedullary NiTi nails (length 26 mm, thickness 1.