Study of the cyto- and genotoxic activity of water from the Kapshagai reservoir (Kazakhstan) on laboratory mice.

Chemical compounds in the environment, which exhibit toxic and genotoxic activity, increase the mutational pressure on biota. This study aimed to investigate the genotoxic, mutagenic, and toxic effects of water from the Ile River and the Kapshagai Reservoir, both sites of active economic activities. Cytogenetic analysis of bone marrow from mice exposed to water samples from the Ile River and the Kapshagai Reservoir revealed a statistically significant increase in aberrant (p<0.

Screening of natural surface waters of the Almaty region of the Republic of Kazakhstan for toxic and mutagenic activity.

Natural aquatic ecosystems are a habitat for many organisms, a source of drinking water, and a resource for human economic activity. However, natural surface waters have been subjected to intense anthropogenic pressure in recent decades. The current study was dedicated to investigating genotoxic potential in 15 rivers and 2 lakes of Almaty agglomeration (Kazakhstan) using a battery of bioassays.

Antimutagenic Properties of Biologically Active Substances of Microalgae Associates.

Introduction: There are an increasing number of different xenobiotics negatively influencing population health. Therefore, it is important to find effective protectors against mutagenic and toxic effects of environmental pollutants. Naturally occurring biologically active substances, the majority of which are antioxidants, are capable of functioning as modifiers of the induced mutation process.

Chromosomal instability in rodents caused by pollution from Baikonur cosmodrome.

An assessment of the health status of ecosystems exposed to man-made pollution is a vital issue for many countries. Particularly it concerns the consequences of contamination caused by the activity of the space industry. Each rocket launch is accompanied by the introduction of parts of the rocket propellant into the environment.