Publications by authors named "Saul Langarica"

Accurate short- and mid-term blood glucose predictions are crucial for patients with diabetes struggling to maintain healthy glucose levels, as well as for individuals at risk of developing the disease. Consequently, numerous efforts from the scientific community have focused on developing predictive models for glucose levels. This study harnesses physiological data collected from wearable sensors to construct a series of data-driven models based on deep learning approaches.

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Article Synopsis
  • The study focuses on thyroid eye disease (TED), which can lead to optic nerve compression, and aims to develop a deep-learning model to analyze CT images of the eye to differentiate between mild and severe cases of TED.
  • Researchers used a U-Net model for automatic segmentation of orbital muscle and fat, achieving high accuracy in volume measurement, with a Dice coefficient of 0.902 for muscle and 0.921 for fat.
  • The machine learning classification model demonstrated an impressive accuracy of 83.8% in distinguishing cases of normal, mild, and severe TED, indicating the potential of this technology for future clinical applications.
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Currently, most reliable and commercialized artificial pancreas systems for type 1 diabetes are hybrid closed-loop systems, which require the user to announce every meal and its size. However, estimating the amount of carbohydrates in a meal and announcing each and every meal is an error-prone process that introduces important uncertainties to the problem, which when not considered, lead to sub-optimal outcomes of the controller. To address this problem, we propose a novel deep-learning-based model for probabilistic glucose prediction, called the Input and State Recurrent Kalman Network (ISRKN), which consists in the incorporation of an input and state Kalman filter in the latent space of a deep neural network so that the posterior distributions can be computed in closed form and the uncertainty can be propagated using the Kalman equations.

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