Does Addition of a Longer Acting Local Anesthetic Improve Postoperative Pain After Carpal Tunnel Release? A Randomized Controlled Trial.

Purpose: Carpal tunnel release (CTR) is a simple and effective treatment for carpal tunnel syndrome in patients who have failed nonsurgical management. This surgery is often performed in the ambulatory clinic under local anesthesia, with lidocaine, a short-acting agent. Few studies have investigated the use of longer acting agents, such as bupivacaine, for outpatient CTR.

Four-Corner Arthrodesis with a Dorsal Locking PEEK Plate: A Retrospective Case Series.

 Four-corner arthrodesis (4CA) can be performed with a variety of methods. To our knowledge, fewer than 125 cases of 4CA with a locking polyether ether ketone (PEEK) plate have been reported, necessitating further study.  The purpose of this study was to evaluate the radiographic union rate and clinical outcomes in a series of patients who received 4CA with a locking PEEK plate.

Extraction of Antioxidants from Juice Using Macroporous Resins.

Antioxidants play a vital role in the human body by defending cells from damage caused by free radicals, highly reactive products of oxidation reactions. A major source of antioxidants is fruits and vegetables. , a breed created at the end of the 19th century by crossbreeding wild and Russian Mountain Ash, produces fruits with one of the highest known content of hydrophilic antioxidants.

The Effects of Patient Resilience and Catastrophizing on Carpal Tunnel Surgical Outcomes.

Purpose: Outcomes following carpal tunnel release (CTR) are generally favorable. When patient satisfaction or symptom resolution is not as expected, understanding what factors contribute to that outcome could allow for strategies targeted at improving results. Our purpose was to determine if measurable mental health factors, specifically resilience and pain catastrophization, correlate with patients' postoperative outcomes following CTR.

Four-Corner Arthrodesis With Differing Methods of Osteosynthesis: A Systematic Review.

Purpose: The purpose of this study was to compare the union rates and clinical outcomes of 4-corner arthrodesis with different methods of osteosynthesis.

Methods: A systematic review of studies published in Ovid, Medline, Embase, and PubMed was conducted. Primary studies that reported clinical and radiographic results following 4-corner arthrodesis for scapholunate advanced collapse (SLAC), scaphoid nonunion advanced collapse (SNAC), or other types of wrist arthritis in human subjects were eligible.

The Effect of Personalized Patient Videos on Patient Satisfaction After Arthroscopic Shoulder Surgery.

Dissatisfaction after shoulder arthroscopy may be influenced by the information that patients receive. Multimedia is an emerging modality of information delivery. The goal of this study was to evaluate whether providing patients with a personalized video of their arthroscopic shoulder surgery improved satisfaction through a multisurgeon randomized controlled study.

Recovery of borderline oxacillin-resistant (BORSP) from bone and soft tissue of a rheumatoid arthritis patient with severe osteoporosis: transmission from the family dog.

We report a case of borderline oxacillin-resistant (BORSP) in a rheumatoid arthritis patient with severe osteoporosis. The organism is also resistant to erythromycin and clindamycin. We also present clear evidence on transmission from the family dog.

Demonstration of an iron fluorescence lidar operating at 372 nm wavelength using a newly-developed Nd:YAG laser.

We report on the development of a pulsed neodymium-doped yttrium aluminum garnet (Nd:YAG) laser operating at a 1116 nm wavelength. Because the third harmonic is within a few gigahertz of the 372 nm absorption line of iron, this laser system represents an alternative to alexandrite lasers commonly used in iron fluorescence lidars. With our prototype, we achieved a 0.

A possible role for CD8+ T lymphocytes in the cell-mediated pathogenesis of pemphigus vulgaris.

Pemphigus vulgaris (PV) is an autoimmune blistering disease whose pathogenesis involves both humoral and cell-mediated immune response. Though the pathogenetic role of autoantibodies directed against desmoglein 3 is certain, a number of other factors have been suggested to determine acantholysis in PV. In this study we examined the possible role of CD8+ T cells in the development of acantholysis by a passive transfer of PV autoantibodies using CD8 deficient mice, and we also studied the inflammatory infiltrate of PV skin lesions by immunohistochemical staining.

Novel use of polymethyl methacrylate (PMMA) microspheres in the treatment of infraorbital rhytids.

Aim: To demonstrate safely with the use of polymethyl methacrylate (PMMA) microspheres in the infraorbital eyelid area using a deliberate conservative injection in the treatment of rhytids.

Methods: A retrospective case series of 289 patients in an outpatient cosmetic dermatology clinic evaluated and treated by one senior provider (NM) of infraorbital rhytids with PMMA from December 2010 to March 2011. Statistical analysis was performed for race, skin type, history of hypertrophic scar, autoimmunity, history of "sensitive skin" and history of prior procedures such as prior facelift, rhinoplasty, and blepharoplasty.

A recombinant human hyaluronidase sustained release gel for the treatment of post-surgical edema.

Background: Edema commonly accompanies surgical procedures and when excessive, can adversely affect surgical outcomes. The skin extracellular matrix, including one of its primary components, hyaluronan (HA), is a significant barrier to effective drainage of accumulated edematous fluid. Recombinant human hyaluronidase (rHuPH20) is a human hyaluronidase that acts transiently and locally to depolymerize HA.

Squamous cell carcinoma manifesting as cutaneous cystic lesions.

Squamous cell carcinoma (SCC), a malignancy of epidermal keratinocytes, is the second most common cause of skin cancer in the United States. Our case represents an unusual variant of this common tumor. We report a clinical presentation of a case of SCC occurring as cutaneous cystic lesions on the face of an 87-year-old white woman with a medical history of multiple SCCs.

A comparison of two headless compression screws for operative treatment of scaphoid fractures.

Purpose: The purpose of this study was to compare the interfragmentary compression force across a simulated scaphoid fracture by two commonly used compression screw systems; the Acutrak 2 Standard and the 3.0 mm Synthes headless compression screw.

Methods: Sixteen (8 pairs; 6 female, 2 male) cadaver scaphoids were randomly assigned to receive either the Acutrak 2 or Synthes screw with the contralateral scaphoid designated to receive the opposite.

Perilunate injuries.

Perilunate injuries are complex injuries of the bony and ligamentous structures of the wrist. They require operative management with careful restoration of carpal alignment and open reduction and internal fixation of associated fractures. Even with optimal treatment, mild to moderate dysfunction affects most patients.

Perilunate injuries.

Perilunate injuries are complex injuries of the bony and ligamentous structures of the wrist. They require operative management with careful restoration of carpal alignment and open reduction and internal fixation of associated fractures. Even with optimal treatment, mild to moderate dysfunction affects most patients.

Management of isolated ulnar shaft fractures.

Isolated fractures of the ulnar shaft are common forearm injuries. Although seemingly benign, they may be complicated by nonunion, radioulnar synostosis, and loss of motion. Unstable fractures are those that are displaced more than 50 percent, angulated more than 10 degrees, or are located in the proximal third of the ulna.

Hemiarthroplasty of the distal ulna with an eccentric prosthesis.

Replacement arthroplasty of the ulnar head is indicated primarily for stiffness and pain as a consequence of rheumatoid, degenerative, and posttraumatic arthritis of the distal radioulnar joint. It is also successfully used in the setting of previous failed excisional arthroplasty of the distal ulna. A distal ulnar hemiarthroplasty, which anatomically recreates the native ulnar head by employing an eccentric design, is discussed.

Laser operation at 1.3microm of 2at.% doped crystalline Nd:YAG in a bounce geometry.

High efficiency and high power laser operation of highly-doped 2at.% crystalline Nd:YAG at 1.3microm is demonstrated in a diode-side pumped bounce amplifier configuration.

Over 40-watt diffraction-limited Q-switched output from neodymium-doped YAG ceramic bounce amplifiers.

High power operation of high repetition Q-switched ceramic Nd:YAG laser is demonstrated using a master-oscillator power amplifier with a transversely-pumped bounce geometry. The laser system produced >40W high spatial quality output (M(2) <1.3) at a pulse repetition frequency of >100kHz.

Nested, non-parametric, correlative analysis of microarrays for heterogenous phenotype characterization.

We present a non-parametric approach for qualitatively selecting candidate genes to characterize several criteria that are nested among genes selected on the basis of their individual, similar effects upon an array-wide closeness measure. In this setting, a goal is to obtain a reliable characterization of phenotypes, based on very high-dimensional data from a few samples. As opposed to a distance-based approach, the proposed measure defines closeness based on gene signal profiles (functionals) rather than on isolated (numerical) differences in each gene between samples.

Photoaging: mechanisms and repair.

Unlabelled: Aging is a complex, multifactorial process resulting in several functional and esthetic changes in the skin. These changes result from intrinsic as well as extrinsic processes, such as ultraviolet radiation. Recent advances in skin biology have increased our understanding of skin homeostasis and the aging process, as well as the mechanisms by which ultraviolet radiation contributes to photoaging and cutaneous disease.

Pemphigus vulgaris induced by electrical injury.

Pemphigus refers to a group of autoimmune blistering diseases that affect the skin and mucous membranes. Pemphigus may be induced following exposure to various exogenous agents, including thermal burns, drugs, infectious agents, and neoplasms, as well as UV, ionizing, and x-ray irradiation. We report a case of a 28-year-old man with pemphigus vulgaris (PV) induced by a severe electrical injury.