Effect of Er,Cr:YSGG on bond strength and microleakage of dentin bonded to resin composite with different distance and irradiation time.

Background: To explore the surface modification of dentin using Er,Cr:YSGG phototherapy and bonding system on the shear bond strength and microleakage scores at two different distances and times of laser irradiation.

Materials And Methods: Ninety disease-free third molars were collected for the experiment. The four laser groups were divided on the basis of non-contact mode distance and time of irradiation: Group-I: Distance of 1 mm with duration of 60 s; Group-II: Distance of 1 mm with duration of 120 s; Group-III: Distance of 2 mm with duration of 60 s and; Group-IV: Distance of 2 mm with duration of 120 s.

Effects of platelet-derived growth factor, vitamin D and parathyroid hormone on osteoblasts derived from cancer patients on chronic bisphosphonate therapy.

Bisphosphonates consist of a family of pyrophosphate analogues that are currently being used to treat metastatic bone diseases as well as systemic bone diseases such as osteoporosis. There is accumulating evidence suggesting that patients treated with these bisphosphonates can develop, particularly with invasive dental procedures, osteonecrosis of the jaw. This present study investigated the ability of osteoblastic cells obtained from the alveolar bone of patients on long term intravenous bisphosphonate therapy to respond to agents normally involved in bone regulation and repair.