Elevated Troponin T (TnT) in Non-acute Coronary Syndrome (ACS) Due to Dermatomyositis.

Troponin is a highly specific biomarker for myocardial injury. It plays a critical role in the diagnosis of acute coronary syndrome (ACS). However, elevated troponin levels are not exclusively due to cardiac ischemia and may be observed in many non-cardiac conditions, including inflammatory myopathies.

Pathological roles of lncRNA HOTAIR in liver cancer: An updated review.

Liver cancer ranks as the sixth most prevalent form of cancer and stands as the fourth leading cause of cancer-related fatalities on a global scale. The two primary types of liver cancer are hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC). While ICC originates from the bile ducts, HCC develops from hepatocytes, which are the primary functional cells of the liver.

Anatomy of a hotspot: Cisplatin hotspots in the tdk gene of Escherichia coli.

We previously reported that certain sub-regions of the thyA gene of Escherichia coli are more mutable than others when many different mutagens and mutators are analyzed (Mashiach et al., Mutation Research Fundamental Molecular Mechansims of Mutagenesis, 821: 111702, 2021). In this study, we focus on a single mutagen, cisplatin and verify that mutations occur preferentially at specific 3 bp sequences, but only when they appear in certain subregions of the gene.

Synthesis, characterization, and applications of starch-based nano drug delivery systems for breast cancer therapy: A review.

The review examined the potential of starch-based drug delivery systems for managing breast cancer efficiently. It covered the background of breast cancer and the significance of drug delivery systems in treatment enhancement. Starch, known for its versatile physicochemical properties, was explored as a promising biopolymer for drug delivery.

Complications and Revision Surgery in Orthopedics Focusing on Traumatology.

Background: Orthopedic traumatology, a vital component of orthopedic surgery, poses significant challenges in managing complications and necessitating revision surgeries. These challenges impact clinical outcomes, healthcare economics, and patient well-being.

Objective: This study aimed to provide insights that informed clinical decision-making and improved patient outcomes by thoroughly examining the range of complications encountered in orthopedic traumatology.

Thrombocytopenia following iron repletion with ferrous gluconate.

Immune thrombocytopenia (ITP) is an autoimmune disorder marked by low platelet counts that puts patients at risk for spontaneous bleeding. A rare trigger for ITP is iron repletion, which has only been reported in a few cases. In this article, we present a unique case of a 54-year-old male with a history of recurrent ITP who experienced rapid thrombocytopenia following iron repletion with ferrous gluconate.

Progress in the Sustainable Development of Biobased (Nano)materials for Application in Water Treatment Technologies.

Water pollution remains a widespread problem, affecting the health and wellbeing of people around the globe. While current advancements in wastewater treatment and desalination show promise, there are still challenges that need to be overcome to make these technologies commercially viable. Nanotechnology plays a pivotal role in water purification and desalination processes today.

Cost-effective in-house COVID-19 reverse transcription-polymerase chain reaction testing with yeast-derived polymerase.

Background: Despite the decline of the COVID-19 pandemic, there continues to be a persistent requirement for reliable testing methods that can be adapted to future outbreaks and areas with limited resources. While the standard approach of using reverse transcription-polymerase chain reaction (RT-PCR) with polymerase is effective, it faces challenges such as limited access to high-quality enzymes and the presence of bacterial DNA contamination in commercial kits, which can impact the accuracy of test results.

Methods: This study investigates the production of recombinant polymerase in yeast cells and assesses its crude lysate in a multiplex RT-PCR assay for detecting the SARS-CoV-2 RNA-dependent RNA polymerase and genes, with human serving as an internal control.

Emerging Perspectives on the Impact of Diabetes Mellitus and Anti-Diabetic Drugs on Premenstrual Syndrome. A Narrative Review.

Diabetes mellitus (DM) and premenstrual syndrome (PMS) are global health challenges. Both disorders are often linked to a range of physical and psychological symptoms that significantly impact the quality of life of many women. Yet, the exact relation between DM and PMS is not clear, and the management of both conditions poses a considerable challenge.

Potential acetylcholinesterase inhibitors to treat Alzheimer's disease.

Objective: Alzheimer's disease (AD) is identified by neuropathological symptoms, and there is now no effective treatment for the condition. A lack of the brain neurotransmitter acetylcholine has been related to the etiology of Alzheimer's disease. Acetylcholinesterase is an enzyme that breaks down acetylcholine to an inactive form and causes the death of cholinergic neurons.

The successful treatment of mpox with brincidofovir in renal transplant recipients-a report of 2 cases.

An mpox outbreak was declared in July 2022 by the world health organization (WHO). It causes a mild self-limiting disease however; in immunosuppressed hosts, it tends to cause severe disseminated infection. Most cases of mpox in sold organ transplant (SOT) recipients reported in the literature were treated with tecovirimat.

Undiagnosed Celiac Disease Associated With Antiphospholipid Syndrome Causing Infertility and Osteoporosis.

Celiac disease and antiphospholipid syndrome are two conditions associated with infertility, but their coexistence is rarely reported. In this manuscript, we present the case of a 23-year-old woman initially presenting with urticaria and vitamin D deficiency, subsequently developing recurrent miscarriages and osteoporosis over a period of 13 years. After initially presenting with urticaria and vitamin D deficiency, she was diagnosed with idiopathic urticaria.

Removal of heavy metals from wastewater by aerogel derived from date palm waste.

Cellulose that has been sourced from date palm leaves as a primary component was utilised. This cellulose served as the foundational material for the development of an aerogel composite. During this process, MXene (TiCT) played a pivotal role in enhancing the overall composition of the aerogel.

Handheld Lung Ultrasound to Detect COVID-19 Pneumonia in Inpatients: A Prospective Cohort Study.

: Chest imaging, including chest X-ray (CXR) and computed tomography (CT), can be a helpful adjunct to nucleic acid test (NAT) in the diagnosis and management of Coronavirus Disease 2019 (COVID-19). Lung point of care ultrasound (POCUS), particularly with handheld devices, is an imaging alternative that is rapid, highly portable, and more accessible in low-resource settings. A standardized POCUS scanning protocol has been proposed to assess the severity of COVID-19 pneumonia, but it has not been sufficiently validated to assess diagnostic accuracy for COVID-19 pneumonia.

Prevalence of Nonalcoholic Fatty Liver Disease at a Tertiary Care Center in Saudi Arabia.

Objectives: To determine the prevalence of nonalcoholic fatty liver disease (NAFLD) in patients who received abdominal imaging and to assess the clinical and metabolic characteristics of NAFLD.

Methods: This is a retrospective study of 500 family medicine patients (aged 18 years and older) who completed abdominal imaging at King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia, from January 2016 through June 2020.

Results: The patients enrolled had a mean age of 49.

The Differences in the Practice of Cosmetic Dermatologic Procedures Between Physicians and Nonphysicians.

Background: With a rise in demand for cosmetic dermatologic procedures comes an increase in nonphysician providers performing such procedures. However, little is known about the practice of cosmetic procedures performed by nonphysicians.

Objective: To assess the differences in the practice of cosmetic procedures provided by physicians and nonphysicians.

Point-of-care AI-assisted stepwise ultrasound pneumothorax diagnosis.

. Ultrasound is extensively utilized as a convenient and cost-effective method in emergency situations. Unfortunately, the limited availability of skilled clinicians in emergency hinders the wider adoption of point-of-care ultrasound.

The Impact of Continuity of Care on Health Indicators in Patients With Type 2 Diabetes Mellitus in Family Medicine Clinics in Riyadh.

Background: Diabetes Mellitus Type 2 (DM2) is highly prevalent in Saudi Arabia, with many experiencing complications due to the disease. Family medicine physicians are usually the primary care providers responsible for the medical management of type 2 diabetes mellitus patients. Microvascular and macrovascular complications can occur if type 2 diabetes mellitus is poorly managed.

Relationship between body mass index and mortality of burns patients: A systematic review and meta-analysis.

This systematic review and meta-analysis aimed to evaluate the relationship between body mass index (BMI) and mortality of burn patients. A comprehensive, systematic search was conducted in different international electronic databases, such as Scopus, PubMed, Web of Science and Persian electronic databases such as Iranmedex, and Scientific Information Database (SID) using keywords extracted from Medical Subject Headings such as "Body mass index", "Burns" and "Mortality" from the earliest to the April 1, 2023. The quality of the studies included in this systematic review was evaluated using the appraisal tool for cross-sectional studies (AXIS tool).

Sustainable Preparation of Graphene Quantum Dots from Leaves of Date Palm Tree.

The date palm (), a subtropical and tropical tree, included in the family () is one of the oldest cultivated plants of mankind. Date palm is a major agricultural product in the semi-arid and arid areas of the world, particularly in Arab countries. These trees generate high quantities of agricultural waste in the form of dry leaves, seeds, etc.