Publications by authors named "Satya Ranjan Singh"
is a nosocomial pathogen with a high potential to cause food-borne infections. It is designated as a critical pathogen by the World Health Organization due to its multi-drug resistance and mortalities reported. Biofilm governs major virulence factors, which promotes drug resistance in .
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- - The study developed cobalt (II) metal ion hybrids with phyto-flavonol galangin and aryl diazenyl coumarins, utilizing various spectral techniques for structural confirmation.
- - Therapeutic potential was assessed using predictive models and molecular simulations, revealing strong activities as kinase inhibitors and antischistosomal agents, with promising docking scores suggesting potential as anticancer inhibitors.
- - The top two ligands displayed favorable drug-like properties and low toxicity, highlighting the feasibility of integrating phytochemicals into therapeutic applications, supported by bioinformatics for early candidate selection.
pH modulates the role of SP6 RNA polymerase in transcription process: an study.
J Biomol Struct Dyn
December 2023
SP6 RNA polymerase (SP6 RNAP) is an essential enzyme for the transcription process in SP6 bacteriophage. SP6 RNAP plays a vital role in mRNA vaccine designing technology and other translational biotechnology research due to the high specificity towards its promoter. The self-replicating performance also put this polymerase to study extensively.
View Article and Find Full Text PDFObesity is considered a global crisis because of its increased risk factors triggered by lifestyle changes. The prevalence of this condition is increasing at an alarming rate, giving rise to development of novel drugs. Pancreatic lipase possesses higher efficacy in inhibiting this condition among the other drug targets.
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