Publications by authors named "Satsuki Fukushima"

Background: With the rapid expansion of transcatheter aortic valve replacement (TAVR), TAVR valve explantation is also increasing. Nevertheless, previous reports on Lotus Edge valve explantation are limited to only two reports, none of which include intraoperative videos. Therefore, we report the case of an older adult who underwent a 2-year-old Lotus Edge valve explantation, after developing prosthetic valve endocarditis (PVE) and aortic annular abscess, with a strong indication for a TAVR explantation and surgical aortic valve replacement (AVR).

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Background: Driveline infections (DLI) caused by nontuberculous mycobacteria (NTM) in patients with implantable left ventricular assist devices (iLVAD) are rare but fatal, requiring early diagnosis and appropriate treatment. Herein, we present a rare case of DLI caused by Mycobacterium chelonae, which was promptly diagnosed using Gram stain and Ziehl-Neelsen stain and followed a favorable clinical course.

Case Presentation: A 51-year-old man with an iLVAD complicated by DLI was admitted to our center.

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Despite the widespread adoption of valve-in-valve transcatheter aortic valve replacement (VIV-TAVR) for patients with failed aortic bioprosthesis, the effectiveness of this treatment for Japanese patients frequently associated with small aortic annuli remains unclear. From December-2011 to October-2022, 41 consecutive patients undergoing VIV-TAVR were enrolled in this study. The endpoints were technical success, device success, early safety, and two-year mortality according to implanted surgical valve size (small valves: 19-mm and 21-mm, n = 23; large valves: 23-mm and 25-mm, n = 18).

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Article Synopsis
  • Peripheral veno-arterial extracorporeal membrane oxygenation (ECMO) can save lives but may cause significant pulmonary edema in heart failure patients; this study highlights better outcomes with a novel central ECMO system that adjusts blood perfusion.!* -
  • Analyzed 10 patients with severe heart failure and pulmonary edema treated using the RALV-AOPA ECMO, which provided optimized blood flow patterns and lower pulmonary arterial pressure, leading to improved heart function within 24 hours.!* -
  • Six patients improved enough to be weaned off ECMO, while others received heart devices or transplants; all patients survived long-term with manageable complications, showcasing the central ECMO system's effectiveness in critical cases.!*
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Objectives: The goal of this study was to investigate whether a larger prosthetic ring relative to a patient's body surface area (BSA) is associated with an increased risk of tricuspid regurgitation (TR) recurrence after tricuspid annuloplasty and of adverse effects on long-term outcomes.

Methods: We retrospectively enrolled 239 patients who underwent tricuspid ring annuloplasty and mitral valve surgery between 2011 and 2016. The tricuspid annuloplasty ring index (TARI) was calculated by dividing the size of the annuloplasty ring (mm) by the BSA (m2).

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Unlabelled: We present a case of BK polyomavirus (BKV) nephropathy (BKVN) after heart transplantation (HTx). The patient was a male with non-ischemic cardiomyopathy who received HTx at the age of 56 years [serum creatinine (sCre) at the time of HTx: 0.89 mg/dl].

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  • - Takayasu arteritis (TAK) is a serious condition that affects large blood vessels, leading to issues like blockages and aneurysms; it's primarily treated with glucocorticoids, but new biological drugs like tocilizumab are proving effective.
  • - Patients on tocilizumab may face higher surgical complications, such as infection or delayed healing, and typically do not show increased inflammatory markers during infections, making management challenging.
  • - There is a lack of guidelines for the best perioperative care for TAK patients needing cardiovascular surgery, but this article proposes a protocol based on recent evidence to help reduce complications in these patients.
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  • The study explored the timing for surgery in patients with asymptomatic or slightly symptomatic chronic severe aortic regurgitation but with normal heart function, involving 210 patients to assess treatment plans and outcomes.
  • In two distinct studies, one group (Study A) followed a watchful waiting approach, revealing that survival rates matched those of the general population, while another group (Study B) evaluated surgical outcomes after aortic valve replacement, highlighting certain risks associated with heart chamber size.
  • The findings suggest that watchful waiting is a safe option, but left ventricular size over 45 mm before surgery is a key indicator of poor postoperative results, potentially guiding future treatment decisions.
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  • Early use of EcMELLA has shown better outcomes, but guidelines for its use are still unclear, especially concerning risks related to access routes and contraindications like left ventricular thrombosis.
  • In a case study, a 74-year-old patient with heart failure and left ventricular thrombosis successfully received a single-access EcMELLA treatment after surgery, leading to significant recovery and discharge after 31 days.
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Background: Coronavirus disease 2019 (COVID-19) is predominantly known to cause respiratory injury; however, the present case series highlights four instances in which the infection resulted in significant cardiac complications. Among such cases, some represent severe cardiogenic shock, which necessitates the immediate introduction of mechanical circulatory support (MCS) for salvage.

Case Summary: This case series involved patients with COVID-19-associated myocardial injury leading to fulminant cardiogenic shock.

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The 2018 Osaka earthquake caused severe damage to the National Cerebral and Cardiovascular Center, and the interruption to the delivery of hospital food in particular had a significant effect on patients with left ventricular assist devices (LVAD). We retrospectively assessed 10 patients who had been provided with emergency rations on the day of earthquake and the next day for breakfast. Catered foods were provided thereafter.

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Background And Purpose: Anticoagulant therapy with vitamin K antagonists is recommended within 3 to 6 months after bioprosthetic valve replacement to prevent thromboembolic events. However, data regarding whether direct oral anticoagulants can be an alternative to warfarin in such patients are limited. The purpose of this study is to compare the efficacy and safety of edoxaban versus warfarin within 3 months after bioprosthetic valve replacement.

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Background: Concomitant tricuspid valve (TV) repair is a safe and effective procedure to protect against late moderate or greater tricuspid regurgitation (TR) after left-sided valve surgery, but studies regarding its late outcomes and recurrent TR are limited. This study aimed to reveal the late outcomes and explore the predictors of mortality and recurrent TR among patients who underwent concomitant TV repair with left-sided valve surgery.

Methods And Results: This study included 645 patients (mean age, 69.

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Background: Transcatheter aortic valve replacement (TAVR) has become widely used in recent years, However, there is also an increasing need for removal of TAVR valves due to prosthetic valve dysfunction (PVD) and the development of infective endocarditis. Surgical aortic valve replacement (AVR) for these patients is risky due to the original patient background and anatomic conditions. Intuity rapid deployment aortic valve (Edwards Lifesciences, Irvine, CA) replacement would be useful for such high risk patients to prevent longer cardiac arrest time and obtain good hemodynamic results.

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Background: Left ventricular (LV) decompression is an essential strategy for improving early survival in patients with refractory cardiogenic shock. Low pump flow in patients on extracorporeal life support (ECLS) with LV apex decompression is a life-threatening issue. However, identifying the underlying causes of low flow can be challenging.

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Since 2011, implantable ventricular assist devices have been a standard treatment for severe heart failure alongside heart transplantation in Japan. However, the limited availability of donors has led to a prolonged wait for transplants, now averaging 1719 days, intensifying the issue of aortic insufficiency in patients with continuous flow ventricular assist devices. These devices limit the opening of the aortic valve, leading to sustained closure and increased shear stress, which accelerates valve degradation.

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Aims: Although systolic expansion of the annulus has been recognized in Barlow's disease, the mechanisms of the unique pathological movement of the annulus and its relation to the leaflet augmentation have not yet been clarified. We aimed to investigate the detailed mechanisms of the characteristic mitral apparatus dynamics in Barlow's disease by frame-by-frame sequential geometric analysis using real-time 3D transoesophageal echocardiography.

Methods And Results: Fifty-three patients with Barlow's disease and severe mitral regurgitation without torn chordae, as well as 10 controls, were included.

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Background: This study investigated whether intraoperative blood salvage was associated with coagulation disorder diagnosed by conventional coagulation tests and thromboelastography (TEG) after cardiopulmonary bypass (CPB).

Study Design And Methods: This was a prospective, observational study. Ninety-two patients who underwent cardiovascular surgery with CPB were enrolled.

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Article Synopsis
  • This study investigates whether fibrosis in right ventricular endomyocardial biopsies can predict the extent of fibrosis in the left ventricle for patients with dilated cardiomyopathy (DCM).
  • A comparison was made between 70 RV biopsy specimens and the left ventricle of 70 excised hearts, showing a strong correlation in fibrosis levels.
  • The findings suggest that analyzing RV biopsies could provide a non-invasive way to estimate left ventricular fibrosis, which is crucial for assessing patient prognosis in DCM.
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There are no criteria for surgical mechanical circulatory system (MCS) selection for acute heart failure. Since 2021, we have utilized cardiopulmonary bypass system to assess patients' heart and lung condition to inform surgical MCS selection. we aimed to retrospectively analyze the outcomes of treatments administered using our protocol.

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