Orbital metastasis of invasive lobular carcinoma of the breast.

We herein report a case of orbital metastasis from the breast cancer in a 58-year-old woman presenting with visual disturbance and bilateral periorbital swelling. She had undergone radical mastectomy for right breast cancer 9 years previously and been receiving hormone therapy for bone metastasis of breast cancer for the past 4 years. Computed tomography and magnetic resonance imaging revealed an ill-defined mass in the bilateral orbits, whereas an excisional biopsy confirmed metastasis of invasive lobular carcinoma (ILC) of the breast.

A Comparison of the Corrected Intraocular Pressure Obtained by the Corvis ST and Reichert 7CR Tonometers in Glaucoma Patients.

The purpose of the study was to investigate the accuracy of two corrected intraocular pressure (IOP) measurements by Corvis Scheimpflug Technology (CST)-IOPpachy and by corneal-compensated IOP (IOPcc) using the Reichert 7CR (7CR) tonometers. We also investigated the effects of corneal anatomical and structural parameters on the IOP measurements. The participants included 90 primary open-angle glaucoma patients.

hCAS/CSE1L regulates RAD51 distribution and focus formation for homologous recombinational repair.

Homologous recombinational repair (HR) is one of the major repair systems for DNA double-strand breaks. RAD51 is a key molecule in HR, and the RAD51 concentration in the cell nucleus increases after DNA damage induction. However, the mechanism that regulates the intracellular distribution of RAD51 is still unclear.

Morphological features and important parameters of large optic discs for diagnosing glaucoma.

Purpose: To compare the optic disc parameters of glaucomatous eyes to those of non-glaucomatous eyes with large discs.

Methods: We studied 225 consecutive eyes with large optic discs (>2.82 mm2): 91 eyes with glaucoma and 134 eyes without glaucoma.

Clinical manifestations and treatment of retinoblastoma in Kobe children's hospital for 16 years.

Purpose: To report the clinical manifestations and therapeutic outcomes of retinoblastoma during 16 years.

Methods: Forty-three eyes of 34 patients with retinoblastoma from 1996 to 2011 were retrospectively examined for eye preservation rates based on the disease stage, and the treatment outcomes between monocular and binocular cases were compared. In addition, the relationship between age at initial examination and disease stage and the difference of age at enucleation with or without preservation therapy were examined.

Using the early postoperative intraocular pressure to predict pressure control after a trabeculectomy.

Purpose: The goal of this study was to identify the early postoperative intraocular pressure (IOP) that predicts low pressure control after a trabeculectomy with mitomycin C.

Materials And Methods: This study retrospectively analyzed the medical records of the initial trabeculectomy with mitomycin C in patients with primary open-angle glaucoma. We established 2 target postoperative IOPs, ≤11 and ≤15 mm Hg.

Magnetic resonance imaging-determined subretinal fluid volume in an uveitic patient.

Purpose: To describe the usefulness of the magnetic resonance imaging-determined subretinal fluid volume to evaluate the therapeutic effect on the retinal detachment caused by uveitis with the clouded media.

Methods: We obtained the images by half-Fourier single-shot rapid acquisition with relaxation enhancement magnetic resonance imaging using a microscopy coil. We measured the area of subretinal fluid on each image and calculated the volume of subretinal fluid by multiplying the total area by the slice thickness.

Association of viral isolates from stool samples with intussusception in children.

Background: Intussusception is the most common cause of intestinal obstruction in young children. The pathogenesis of intussusception is still not well understood. In this study the pathogens from stool specimens were investigated in children with intussusception.