Publications by authors named "Satoshi Numa"
Article Synopsis
- Smoking is linked to increased stroke risk in patients with atrial fibrillation (AF), particularly through its effects on the left atrium and aortic health.
- A study involving 122 patients with AF found that current smokers exhibited more severe aortic atherosclerosis compared to non-smokers, though environmental smokers showed similar risks to non-smokers.
- The research suggests that smoking status, particularly in the context of AF, may influence thromboembolic risk, with environmental smokers showing reduced left atrial appendage flow velocity.
Article Synopsis
- Smoking significantly increases the risk of adverse long-term outcomes in patients with atrial fibrillation (AF), including higher rates of all-cause mortality and stroke-related deaths.
- The study analyzed 426 patients over an average of 5.8 years and found that those with a history of smoking experienced more incidents of intracranial bleeding than non-smokers.
- Persistent smoking was linked to an even greater risk of bleeding and predicted mortality outcomes, highlighting the harmful effects of smoking beyond common cardiovascular risk factors.
Background: There is no clear consensus on thromboprophylaxis in patients with nonvalvular atrial fibrillation (AF) at low-intermediate thromboembolic risk. Although hyperuricemia is a risk factor for cardiovascular diseases, the relationship between serum uric acid (UA) levels and thromboembolic risk has not been fully elucidated in patients with AF.
Methods And Results: Serum UA levels and the score for congestive heart failure, hypertension, age, diabetes mellitus, prior stroke/transient ischemic attack, vascular disease and sex (ie, CHA2DS2-VASc score) were determined in 470 patients with nonvalvular AF who underwent transesophageal echocardiography (TEE) to evaluate their risk of thromboembolism.