Publications by authors named "Satoshi Nakazaki"
Article Synopsis
- * Factors linked to elevated IgG4 included male sex, older age, lower lipid and polyunsaturated fatty acid intake, and higher carbohydrate intake in both genders, with additional specific associations for men related to kidney function and blood sugar levels.
- * The findings suggest that elevated serum IgG4 levels are connected to age, gender, and diet, which may reflect similar patterns seen in IgG4-related disease (IgG4-RD).
Objectives: We aimed to evaluate the association between the change in serum IL-6 during the clinical course of tocilizumab (TCZ) therapy and rheumatoid arthritis (RA) disease activity or occurrence of adverse events.
Methods: General laboratory data including serum IL-6 levels and physical findings were obtained every 4 weeks, and, in addition, at the time when any adverse events occurred.
Results: The proportion achieving Clinical Disease Activity Index (CDAI) remission at 52 weeks was significantly lower in 20 patients with serum IL-6 ≥ 30 pg/ml at 12 weeks than 24 patients with serum IL-6 < 30 pg/ml.