Publications by authors named "Satoshi Kamihata"

Article Synopsis
  • A new hip stem made of carbon fiber-reinforced polyetheretherketone (CFR/PEEK) is being developed to help treat periprosthetic joint infections (PJIs) through an antibiotic release mechanism.
  • In an experimental study with sheep, researchers tested how well the antibiotic vancomycin eluted from the implants and assessed their effectiveness in treating induced PJIs caused by Staphylococcus aureus.
  • Results showed that the implant released about 70% of vancomycin over 21 days, and all successfully infected joints exhibited negative cultures and no signs of infection three weeks after surgery, demonstrating the efficacy of the therapeutic stem.
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Article Synopsis
  • Periprosthetic joint infection (PJI) can occur after total hip replacement, leading to severe complications, prompting the development of a new drug-loaded carbon fiber-reinforced polymer (CFRP) prosthesis that allows for one-stage surgery.
  • The study aimed to analyze how vancomycin, an antibiotic, diffuses from CFRP implants by modifying the mixing ratio of vancomycin paste and the size of holes in the implants.
  • Results showed the best diffusion occurred with a 1:1.4 mixing ratio of vancomycin paste and a 2 mm hole diameter, both in laboratory tests and in a rabbit model, indicating drug release can be optimized by adjusting these parameters.
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Objectives: The functional pelvic plane, which adopts the natural pelvic sagittal tilt in the supine position, is a good reference for determining the cup angle in total hip arthroplasty. However, hip flexion contracture may change pelvic tilt postoperatively by the release of contracture. This study investigated the influence of hip flexion contracture on pelvic sagittal tilt in the supine position.

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We experienced a rare case of carpal tunnel syndrome and rupture of the flexor digitorum profundus tendon to the index finger with a scapholunate advanced collapse wrist. We speculated that the lunate that had extruded into the carpal tunnel compressed the median nerve and caused wear of the flexor tendon following neglected perilunate subluxation. Carpal tunnel release, opponensplasty by palmaris longus tendon transfer, and a bridge graft by a half-slip of the flexor carpi radialis tendon resulted in recovery of pinch function and improvement in numbness of the hand.

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