Publications by authors named "Satoshi Funada"
Background: Medical corporations, which are non-profit organizations that aim to operate hospitals, clinics, or long-term care facilities, account for more than half of all hospital beds and play a central role in the health care system in Japan. However, limited analysis of hospital integration has been performed. Examining the hospital integration trends of medical corporations can provide valuable insights for optimizing health care delivery and resource allocation in Japan.
View Article and Find Full Text PDFBackground And Aims: Night-shift work disturbs sleep and is associated with poor health conditions among workers. We aimed to investigate the association between night-shift work and gambling among workers and the association between night-shift work and problem gambling in working and gambling participants.
Methods: This cross-sectional study used data from an online survey conducted between February 6 and 27, 2023 in Japan.
Importance: Although the cognitive components of behavioral therapy for overactive bladder (OAB) are widely recognized, there is a lack of studies evaluating the effectiveness of multicomponent interventions that include cognitive components as a treatment for OAB.
Objective: To examine the efficacy of a multicomponent intervention in improving health-related quality of life (HRQOL) for women with moderate to severe OAB.
Design, Setting, And Participants: This multicenter, open-label, randomized clinical trial was conducted in Japan among women aged 20 to 80 years who had moderate to severe OAB.
Article Synopsis
- * This study aimed to analyze how different CBT-I components and delivery formats impact treatment outcomes, pulling data from major medical and psychological research databases.
- * The findings indicated that key CBT-I components, such as cognitive restructuring and sleep restriction, significantly improved treatment efficacy, while sleep hygiene education was not found to be essential for success.
Background: Overactive bladder (OAB) is a common chronic and bothersome condition. Bladder training is widely prescribed as a first-line treatment for OAB, but the efficacy has been systematically evaluated for urinary incontinence rather than OAB alone.
Objectives: To evaluate the benefits and harms of bladder training for treating adults with OAB compared to no treatment, anticholinergics, β3-adrenoceptor agonists, or pelvic floor muscle training (PFMT) alone or in combination.
Importance: Since the onset of the COVID-19 outbreak, an extremely high number of studies have been published worldwide, with variable quality. Research trends of highly cited papers may enable identification of influential research, providing insights for new research ideas; it is therefore important to investigate trends and focus on more influential publications in COVID-19-related studies.
Objective: To examine research trends of highly cited studies by conducting a bibliometric analysis of highly cited studies in the previous 2 months about COVID-19.
Detection bias in open-label trials of anticancer drugs: a meta-epidemiological study.
BMJ Evid Based Med
November 2023
Objectives: In anticancer clinical trials, particularly open-label trials, central reviewers are recommended to evaluate progression-free survival (PFS) and objective response rate (ORR) to avoid detection bias of local investigators. However, it is not clear whether the bias has been adequately identified, or to what extent it consistently distorts the results. Therefore, the objective of this study was to evaluate the detection bias in oncological open-label trials by confirming whether local investigators overestimate the PFS and ORR compared with the findings of central reviewers.
View Article and Find Full Text PDFImportance: Current evidence remains ambiguous regarding whether biologics should be added to conventional treatment of rheumatoid arthritis for specific patients, which may cause potential overuse or treatment delay.
Objectives: To estimate the benefit of adding biologics to conventional antirheumatic drugs for the treatment of rheumatoid arthritis given baseline characteristics.
Data Sources: Cochrane CENTRAL, Scopus, MEDLINE, and the World Health Organization International Clinical Trials Registry Platform were searched for articles published from database inception to March 2, 2022.
Objectives: Researchers have identified cases in which newspaper stories have exaggerated the results of medical studies reported in original articles. Moreover, the exaggeration sometimes begins with journal articles. We examined what proportion of the studies quoted in newspaper stories were confirmed.
View Article and Find Full Text PDFArticle Synopsis
- The study analyzed the relationship between nocturia (frequent urination at night) and sleep problems among 8,076 participants from the Nagahama study in Japan, finding that both issues are strongly interrelated.
- Statistically, poor sleep was associated with a 1.85 times higher likelihood of nocturia, while nocturia was linked to a 1.90 times increased chance of experiencing poor sleep.
- Longitudinal results showed that baseline nocturia can lead to new cases of poor sleep, while poor sleep can increase the risk of nocturia, particularly in women and participants under 50 years old.
Article Synopsis
- The study aimed to determine the best length of antibiotic treatment for adults with community-acquired pneumonia (CAP), using a systematic review and meta-analysis of randomized controlled trials.
- A total of nine trials were analyzed, showing that treatment durations of 3 to 9 days were likely just as effective as the standard 10-day course, with the 3-day treatment showing a 75% improvement rate.
- The findings suggest that shorter treatment durations (3-5 days) may provide a better balance of effectiveness and reduced treatment burden for adult patients with CAP.
Background: A new ready-to-drink premixed high-alcohol-content beverage, called strong chū-hai, was launched in Japan, and more recently, in Taiwan and Australia. We aimed to examine the popularity and association of strong chū-hai with individual alcohol use, both of which remained unclear.
Methods: We conducted a cross-sectional study using data from the Japan "Society and New Tobacco" Internet Survey conducted from February 1 to 28, 2022, in Japan.
Objectives: In open-label trials, the details of the adjudicators are essential to evaluate the risk of detection bias. We aimed to describe how the adjudicators of progression-free survival (PFS) and objective response rate (ORR) have been reported in open-label trials of anticancer drugs.
Study Design And Setting: A literature search was conducted using MEDLINE via PubMed.
Background And Objectives: The standardized mean difference (SMD) can be calculated from different mean differences (MDs) and standard deviations (SDs). This study aims to investigate how clinical trials calculated, reported and interpreted the SMD, and to examine the variation between different SMDs.
Methods: We searched the PubMed for randomized controlled trials of general medicine and psychiatry that estimated SMDs.
Objectives: We aimed to develop models to predict new-onset overactive bladder in 5 years using a large prospective cohort of the general population.
Methods: This is a secondary analysis of a longitudinal cohort study in Japan. The baseline characteristics were measured between 2008 and 2010, with follow-ups every 5 years.
Background: An accurate prediction model could identify high-risk subjects of incident Overactive bladder (OAB) among the general population and enable early prevention which may save on the related medical costs. However, no efficient model has been developed for predicting incident OAB. In this study, we will develop a model for predicting the onset of OAB at 5-year in the general population setting.
View Article and Find Full Text PDF