Gen Thorac Cardiovasc Surg
January 2023
Objectives: Sternal retractors utilized during open-heart surgeries through median sternotomy can cause upper rib fractures which sometimes further leads to brachial plexus injury. We aimed to investigate the incidence of brachial plexus injury and upper rib fractures in open-heart surgeries and how these injuries are associated with each other.
Methods: We investigated 1050 cases during the past five years.
Mediastinitis occurs after open heart surgery in a small number of cases. When it occurs, early diagnosis and treatment are important. A 69-year-old male patient suffered from mediastinitis after total aortic arch replacement.
View Article and Find Full Text PDFAnn Thorac Cardiovasc Surg
August 2010
With the exception of myxomas, primary tumors of the heart are very rare. We present here our experience with papillary fibroelastoma in the aortic valve. We could not preserve the aortic valve because of the wide attachment of the tumor to the valve and aortic regurgitation.
View Article and Find Full Text PDFCongenital systemic-to-pulmonary artery fistulas are very rare, with the exception of congenital heart disease and pulmonary sequestration. We describe the first reported case of left internal mammary and bronchial artery to pulmonary artery fistulas associated with bilateral coronary arteries to pulmonary artery fistulas.
View Article and Find Full Text PDFBackground: Our previous studies showed that transfer of hepatocyte growth factor (HGF) gene or transplantation of marrow stromal cells (MSCs) remarkably attenuated neurologic injuries after spinal cord ischemia. We sought to investigate a novel neuroprotective strategy of transplantation of human HGF gene-modified MSCs on ischemic spinal cords.
Methods: Human HGF gene was transferred into MSCs in vitro.
Objective: Thoracic and thoracoabdominal aortic surgery is sometimes complicated by subacute or delayed paraplegia. Pro-inflammatory cytokine interleukin-1 (IL-1) beta has been implicated in extensive inflammation and progressive neurodegeneration after ischemia. Using a rabbit model, we investigated the neuroprotective effects of IL-1 receptor antagonist (IL-1ra) in a temporal fashion.
View Article and Find Full Text PDFObjective: Reactive free radical species are thought to be involved in postoperative neurologic dysfunction after antegrade selective cerebral perfusion in brains with old infarction. We assessed the brain protective effect of prophylactically administered edaravone, a free radical scavenger, for antegrade selective cerebral perfusion in brains with or without old infarction in a canine model.
Methods: A canine model of old cerebral infarction was created by injecting cylindric silicone embolus into the middle cerebral artery.