Publications by authors named "Satoru Oya"
Identification of RCC1-LCK as a novel fusion gene in pediatric erythroid sarcoma.
Pediatr Blood Cancer
September 2022
Article Synopsis
- Erythroid sarcoma is a rare form of myeloid sarcoma with unclear biological characteristics, exemplified by an infant patient diagnosed due to positive glycophorin A tumor cells.
- The patient underwent chemotherapy aimed at acute myeloid leukemia, surgical removal of the tumor, and cord blood transplantation, resulting in complete remission without complications.
- Analysis of the tumor's total transcriptome revealed a new fusion gene (RCC1-LCK) and increased levels of LCK expression, indicating a potential link between LCK overexpression and the development of leukemia.