Tuning Philicity of Dichlorosilylene: Nucleophilic Behavior of the Dichlorosilylene-NHC Complex ClSi-IPr.

Novel unsaturated four-membered ring disilene, 3,3-dichloro-1,2,4,4-tetrakis[di--butyl(methyl)silyl]-Δ-1,2,3,4-trisilagermetene, was synthesized by the ring expansion reaction of the three-membered ring 1-disilagermirene with the silylene-NHC complex ClSi-IPr. The mechanism of the unexpected formation of this compound was verified by high-level density functional theory computations, which revealed n-π as the dominant orbital interaction.

Beneficial effects of long-acting nifedipine on coronary vasomotion abnormalities after drug-eluting stent implantation: The NOVEL study.

Aims: It is widely known that drug-eluting stents (DES) induce coronary vasomotion abnormalities. We have previously demonstrated that chronic treatment with long-acting nifedipine suppresses coronary hyperconstricting responses induced by the first-generation DES (e.g.

Toward a silicon version of metathesis: from Schrock-type titanium silylidenes to silatitanacyclobutenes.

Olefin metathesis is one of the most important industrial processes for the production of alkenes. In contrast, silicon versions of metathesis are unknown given the lack of available silylene transition-metal complexes suitable for [2 + 2] cycloaddition with unsaturated substrates. Here, we report the synthesis of 18-electron titanium silylene complexes featuring different Lewis base ligands and classified on the basis of structural, computational, and reactivity studies as Schrock-type silylene complexes.