Computed tomographic findings and prognosis in thymic epithelial tumor patients.

Objective: To determine which computed tomographic findings are associated with high-risk thymic epithelial tumors and a poor prognosis.

Methods: Computed tomographic findings of thymic epithelial neoplasms were retrospectively evaluated in 75 patients diagnosed with thymic tumor between January 1997 and October 2003. We analyzed the correlation of the computed tomographic findings, histological subtype according to the World Health Organization classification, and the prognosis.

Brain microbleeds and global cognitive function in adults without neurological disorder.

Background And Purpose: Increasing attention has been paid to associations between cognitive dysfunction and brain microbleeds (MBs). Because all previous studies have investigated patients with neurological disorders, we examined subjects without neurological disorder in order to clarify pathogenic relationships.

Methods: A total of 518 consecutive adults without neurological disorder who had undergone health-screening tests of the brain were studied prospectively.

Cancer of unknown primary site: review of consecutive cases at the National Cancer Center Hospital of Japan.

Background: Cancer of unknown primary (CUP) is not a rare clinical entity, accounting for 3%-5% of all solid malignancies.

Methods: We retrospectively reviewed 86 (38 male/48 female) patients with a diagnosis of CUP (exclusive of female patients with adenocarcinoma involving the axillary lymph nodes alone and patients with squamous cell carcinoma of the cervical lymph nodes) who were referred to the National Cancer Center Hospital between April 1996 and October 2002.

Results: The median interval between the first visit to a local community hospital and referral to our hospital was 1 month (range, 1 to 45 months).

[A case of pulmonary Langerhans' cell histiocytosis with liver involvement].

We report a case of pulmonary Langerhans' cell histiocytosis with liver involvement in an adult. An asymptomatic 51-year-old man who had, until his referral to our hospital, been a smoker was suspected on examination to have multiple metastases to the lungs and liver. Chest CT showed multiple micronodules, located predominantly in the upper and middle lung fields.