Publications by authors named "Satomi Koyama"
We report a rare case highlighting the progression of liver disease in a male patient with idiopathic childhood-onset growth hormone (GH) deficiency. The patient was diagnosed with hypopituitarism at six years old and was treated with thyroxine therapy and GH for his short stature, with testosterone added at the age of 15. GH therapy was discontinued when the patient was 18 years old, but thyroid and testosterone treatments continued.
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- Pseudohypoparathyroidism (PHP) is a rare disorder causing symptoms like convulsions and involuntary movements due to resistance to parathyroid hormone, resulting in low calcium levels.
- A case study of a 7-year-old girl showed her involuntary movements were initially misdiagnosed and treated with carbamazepine but led to convulsions and revealed significant underlying electrolyte imbalances and brain calcifications.
- Diagnosis was confirmed via genetic testing, and treatment with calcium and vitamin D resolved her symptoms, highlighting the importance of early blood tests for proper PHP diagnosis in patients with similar movement disorders.
A Boy with Reset Osmostat Who Developed Chronic Hyponatremia due to Hypothalamic Injury Caused By a Giant Arachnoid Cyst.
J Clin Res Pediatr Endocrinol
December 2024
Reset osmostat (RO) is classified as type C among the four subtypes of the syndrome of inappropriate secretion of antidiuretic hormone based on antidiuretic hormone (ADH) secretion. It is characterized by a lower plasma osmolality threshold for ADH excretion when plasma sodium concentration is reduced. We report the case of a boy with RO and a giant arachnoid cyst (AC).
View Article and Find Full Text PDFObjectives: Adiposity rebound (AR) refers to an increase in body mass index (BMI) after a nadir. Early AR, in which AR occurs earlier than five years old, is a risk factor for future obesity and metabolic syndrome, but has not been widely studied in very-low-birth-weight infants (VLBWIs).
Methods: The subjects were VLBWIs born in Dokkyo Medical University NICU from January 2008 to December 2010.
Low serum 25-hydroxyvitamin D level is associated with obesity and atherogenesis in adolescent boys.
Ann Pediatr Endocrinol Metab
March 2022
Purpose: We investigated the relationship of 25-hydroxyvitamin D (25[OH]D) level with obesity and atherosclerosis in Japanese adolescents.
Methods: We examined 492 children (247 boys and 245 girls) aged 12-13 years. The serum 25(OH)D level was compared among underweight, healthy weight, and overweight children.
Article Synopsis
- Atrophic autoimmune thyroiditis (AAT) is an uncommon form of hypothyroidism in children, characterized by the absence of goiter and presence of TSH receptor-blocking antibodies.
- This study aimed to determine the prevalence of these antibodies in children diagnosed with AAT by reviewing data from patients under 15 years old.
- The results showed that 38.8% of the 18 patients tested positive for TSH receptor antibodies, suggesting that AAT may be more prevalent in children than previously thought.
Introduction: The incidence rate of vitamin D deficiency is increasing throughout the world. We measured the incidence rate of vitamin D deficiency and fibroblast growth factor 23 (FGF23) levels in 12- to 13-year-old adolescents in Japan.
Materials And Methods: A total of 492 adolescents (247 boys and 245 girls) from Japanese community enrolled in this study.
Childhood obesity: rapid weight gain in early childhood and subsequent cardiometabolic risk.
Clin Pediatr Endocrinol
October 2020
Article Synopsis
- Dynamic changes in body weight, particularly rapid weight gain in infancy and early childhood, are linked to higher risks of future obesity and related health issues like type 2 diabetes and cardiovascular diseases.
- *Many studies show the significance of weight gain during early years, but there's no clear consensus on which specific growth period is most critical for long-term health risks.
- *Recent evidence emphasizes that toddlers with an unusual increase in body mass index (BMI) before age 3 may face a greater risk of future cardiometabolic problems.
The gut is an extremely complicated ecosystem where micro-organisms, nutrients and host cells interact vigorously. Although the function of the intestine and its barrier system weakens with age, some probiotics can potentially prevent age-related intestinal dysfunction. Lactobacillus delbrueckii subsp.
View Article and Find Full Text PDFThere is concern that vitamin D deficiency is prevalent among children in Japan as well as worldwide. We conducted a nationwide epidemiologic survey of symptomatic vitamin D deficiency to observe its incidence rate among Japanese children. A questionnaire inquiring the number of new patients with vitamin D deficiency rickets and/or hypocalcemia for 3 years was sent to 855 randomly selected hospitals with a pediatrics department in Japan.
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