Publications by authors named "Satoko Takigawa"
Topical tetracyclines, such as minocycline ointment, are frequently used for the treatment of periodontal infection. We investigated the influence of minocycline ointment use on oral bacteria, using supragingival plaque samples from adults who had not taken any antibiotics for 6 months. Initially we investigated the effect of topical minocycline administration on the emergence of tetracycline-resistant oral bacteria in four healthy adults.
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- - Butyric acid is linked to periodontal disease and found in periodontal pockets, prompting research into potential treatments.
- - A study using the Ca9-22 human gingival carcinoma cell line showed that sodium bicarbonate improved cell viability compared to butyric acid alone.
- - Sodium bicarbonate also enhanced ICAM-1 expression, suggesting it could help mitigate periodontal tissue damage caused by butyric acid, despite the study's limitations.