Publications by authors named "Satoko Satoh"

Hypertension is one of the most serious side effects of glucocorticoid therapy. We retrospectively investigated the frequency of hypertension during treatment of adrenal crisis and analyzed the factors associated with its development. Patients who were admitted for primary hypoadrenalism due to diagnosed or suspected adrenal crisis were included.

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Indium-111 ((111)In) has a strong binding affinity for transferrin (Tf), and the (111)In-Tf complex binds to Tf receptor in various tissues. In partial hepatectomy (PH), a part of blood in circulation is lost along with removed liver tissues; consequently, the number of blood cells and the amount of Tf in circulation decreases. These decreases should greatly affect the uptake of (111)In in the liver and bone marrow.

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Article Synopsis
  • (67)Ga binds to transferrin and is transported to tissues; this study investigates its uptake in the liver after partial hepatectomy (PH) compared to blood loss from venesection.
  • In rats, both PH and venesection resulted in decreased blood cells and transferrin levels, but the effects on (67)Ga uptake differed between the two methods.
  • After PH, the liver showed a significant increase in (67)Ga uptake, while reticulocytes (immature red blood cells) did not; the opposite occurred after venesection, highlighting the role of transferrin receptors in these processes.
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