Successful Reversal of Refractory Posttransplant Thrombotic Microangiopathy with Eculizumab.

Posttransplant thrombotic microangiopathy (PT-TMA) can be caused by calcineurin inhibitors (CNIs), ischemic injury, infections, or antibody-mediated rejection (ABMR). Delayed recognition can result in allograft loss. We describe the first reported case of successful reversal of refractory PT-TMA with eculizumab in India.

Burden of respiratory illnesses in pediatric intensive care unit and predictors of mortality: Experience from a low resource country.

Introduction And Objectives: Acute respiratory infections (ARI), a major cause of childhood mortality and morbidity, place substantial burden on health services worldwide. Due to scarce data regarding respiratory illnesses requiring Pediatric intensive care unit (PICU) admissions (especially in low income/developing countries), we studied the burden of respiratory illnesses in the PICU and the risk factors contributing to mortality.

Methods: This prospective observational study was conducted over 18 months.